Skip to content
Use your HSA or FSA funds

Gene

CTSB

cathepsin B

Summary

Cytogenetic location
8p23.1
Coordinates
Chromosome 8: 11,842,524–11,868,087 (GRCh38)
Exons
10 exons across 25.6 kb
Protein
339 amino acids
MANE Select transcript
ENST00000353047.11NM_001908.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CTSB yet. The test sequences your whole genome, so your data includes it all the same.

How CTSB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where CTSB sits. CTSB and 15 genes near it on chromosome 8, from 11,355,306 to 12,355,305.Chromosome 88p23.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.311.4 Mb11.6 Mb11.8 Mb12 Mb12.2 MbFAM167A: 11,419,202–11,475,908, reverse strandFAM167ABLK: 11,486,894–11,564,599, forward strandBLKGATA4: 11,676,785–11,763,223, forward strandGATA4NEIL2: 11,769,633–11,787,346, forward strandNEIL2FDFT1: 11,795,565–11,846,085, forward strandFDFT1CTSB: 11,842,524–11,868,087, reverse strandCTSBDEFB136: 11,973,937–11,974,599, reverse strandDEFB136DEFB135: 11,982,256–11,984,590, forward strandDEFB135DEFB134: 11,993,174–12,000,752, reverse strandDEFB134DEFB130B: 12,064,389–12,071,747, reverse strandDEFB130BZNF705D: 12,089,338–12,115,516, forward strandZNF705DUSP17L7: 12,132,417–12,134,099, reverse strandUSP17L7USP17L2: 12,136,435–12,138,849, reverse strandUSP17L2DEFB109D: 12,150,888–12,158,033, reverse strandDEFB109DFAM86B1: 12,182,096–12,194,168, reverse strandFAM86B1DEFB130A: 12,310,962–12,318,316, reverse strandDEFB130ADiagram of CTSB: 10 exons on the reverse strand of chromosome 8Exon 10: 11,842,524–11,845,222, 2,699 basesExon 9: 11,845,661–11,845,789, 129 basesExon 8: 11,847,052–11,847,168, 117 basesExon 7: 11,847,679–11,847,822, 144 basesExon 6: 11,848,067–11,848,152, 86 basesExon 5: 11,849,046–11,849,164, 119 basesExon 4: 11,850,866–11,850,980, 115 basesExon 3: 11,852,610–11,852,695, 86 basesExon 2: 11,853,329–11,853,479, 151 basesExon 1: 11,868,001–11,868,087, 87 bases10864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 25.6 kb; 1,020 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). CTSB gene: cathepsin B. Retrieved 16 October 2026, from https://dantelabs.com/genes/ctsb

Vancouver

Dante Labs. CTSB gene: cathepsin B [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ctsb

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test