Trait
Bone infection
Clinical name: Osteomyelitis
Osteomyelitis is an inflammatory process accompanied by bone destruction and caused by an infecting microorganism.
Reference genomeGRCh38hg38
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Get my Genome Test67 genes linked to Bone infection
Changes in these genes cause rare conditions in which Bone infection is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCC8ATP binding cassette subfamily C member 8 | Always | In 1 condition |
| COPZ1coat protein complex I subunit zeta 1 | Always | In 1 condition |
| CYBBcytochrome b-245 beta chain | Always | In 1 condition |
| EN1engrailed homeobox 1 | Always | In 1 condition |
| GATA2GATA binding protein 2 | Always | In 1 condition |
| IL1R1interleukin 1 receptor type 1 | Always | In 1 condition |
| IL1RNinterleukin 1 receptor antagonist | Always | In 1 condition |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Always | In 1 condition |
| RELREL proto-oncogene, NF-kB subunit | Always | In 1 condition |
| TBK1TANK binding kinase 1 | Always | In 1 condition |
| TMEM63Btransmembrane protein 63B | Always | In 1 condition |
| CLCN7Cl-/H+ antiporter 7 | Very often (80–99%) | In 2 conditions |
| HLA-Bmajor histocompatibility complex, class I, B | Very often (80–99%) | In 1 condition |
| HPGD15-hydroxyprostaglandin dehydrogenase | Very often (80–99%) | In 1 condition |
| LPIN2lipin 2 | Very often (80–99%) | In 2 conditions |
| NTRK1neurotrophic receptor tyrosine kinase 1 | Very often (80–99%) | In 2 conditions |
| SLCO2A1solute carrier organic anion transporter family member 2A1 | Very often (80–99%) | In 1 condition |
| BLNKB cell linker | Often (30–79%) | In 1 condition |
| CD79ACD79a molecule | Often (30–79%) | In 1 condition |
| CD79BCD79b molecule | Often (30–79%) | In 1 condition |
| CLTCL1clathrin heavy chain like 1 | Often (30–79%) | In 1 condition |
| HBBhemoglobin subunit beta | Often (30–79%) | In 1 condition |
| IGHMimmunoglobulin heavy constant mu | Often (30–79%) | In 1 condition |
| IGLL1immunoglobulin lambda like polypeptide 1 | Often (30–79%) | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Often (30–79%) | In 1 condition |
| LRRC8Aleucine rich repeat containing 8 VRAC subunit A | Often (30–79%) | In 1 condition |
| PIGHphosphatidylinositol glycan anchor biosynthesis class H | Often (30–79%) | In 1 condition |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Often (30–79%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Often (30–79%) | In 1 condition |
| RFX5regulatory factor X5 | Often (30–79%) | In 1 condition |
| SPI1Spi-1 proto-oncogene | Often (30–79%) | In 1 condition |
| SPTLC2serine palmitoyltransferase long chain base subunit 2 | Often (30–79%) | In 2 conditions |
| TCF3transcription factor 3 | Often (30–79%) | In 1 condition |
| ATL1atlastin GTPase 1 | Sometimes (5–29%) | In 2 conditions |
| ATL3atlastin GTPase 3 | Sometimes (5–29%) | In 2 conditions |
| ATP7AATPase copper transporting alpha | Sometimes (5–29%) | In 1 condition |
| BTKBruton tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| C2orf69chromosome 2 open reading frame 69 | Sometimes (5–29%) | In 1 condition |
| DOCK8dedicator of cytokinesis 8 | Sometimes (5–29%) | In 1 condition |
| FLVCR1FLVCR choline and heme transporter 1 | Sometimes (5–29%) | In 2 conditions |
Show 27 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| ITGB2integrin subunit beta 2 | Sometimes (5–29%) | In 1 condition |
| MCTS1MCTS1 re-initiation and release factor | Sometimes (5–29%) | In 1 condition |
| NCF2neutrophil cytosolic factor 2 | Sometimes (5–29%) | In 1 condition |
| SCNN1Asodium channel epithelial 1 subunit alpha | Sometimes (5–29%) | In 1 condition |
| SCNN1Bsodium channel epithelial 1 subunit beta | Sometimes (5–29%) | In 1 condition |
| SCNN1Gsodium channel epithelial 1 subunit gamma | Sometimes (5–29%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Sometimes (5–29%) | In 1 condition |
| SPTLC1serine palmitoyltransferase long chain base subunit 1 | Sometimes (5–29%) | In 2 conditions |
| STAT1signal transducer and activator of transcription 1 | Sometimes (5–29%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Sometimes (5–29%) | In 1 condition |
| SYKspleen associated tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| ZNF341zinc finger protein 341 | Sometimes (5–29%) | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Rarely (1–4%) | In 1 condition |
| EFL1elongation factor like GTPase 1 | Rarely (1–4%) | In 1 condition |
| FOXP3forkhead box P3 | Rarely (1–4%) | In 1 condition |
| PGM3phosphoglucomutase 3 | Rarely (1–4%) | In 1 condition |
| PLEKHM1pleckstrin homology and RUN domain containing M1 | Rarely (1–4%) | In 1 condition |
| SBDSSBDS ribosome maturation factor | Rarely (1–4%) | In 1 condition |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Rarely (1–4%) | In 2 conditions |
| ANO5anoctamin 5 | Not recorded | In 1 condition |
| CYBAcytochrome b-245 alpha chain | Not recorded | In 1 condition |
| DNMT1DNA methyltransferase 1 | Not recorded | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Not recorded | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Not recorded | In 1 condition |
| NGFnerve growth factor | Not recorded | In 1 condition |
| RETREG1reticulophagy regulator 1 | Not recorded | In 1 condition |
| TNFSF11TNF superfamily member 11 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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