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Gene

COPZ1

coat protein complex I subunit zeta 1

Summary

Cytogenetic location
12q13.13
Coordinates
Chromosome 12: 54,325,131–54,351,846 (GRCh38)
Exons
9 exons across 26.7 kb
Protein
177 amino acids
Also known as
CGI-120
Previous symbols
COPZ
MANE Select transcript
ENST00000262061.7NM_016057.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads COPZ1 yet. The test sequences your whole genome, so your data includes it all the same.

How COPZ1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 12, with a bracket where COPZ1 sits. COPZ1 and 24 genes near it on chromosome 12, from 53,838,489 to 54,838,488.Chromosome 1212q13.13p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3354 Mb54.2 Mb54.4 Mb54.6 Mb54.8 MbHOXC13: 53,938,718–53,946,544, forward strandHOXC13HOXC12: 53,954,903–53,958,956, forward strandHOXC11: 53,973,126–53,977,643, forward strandHOXC10: 53,985,065–53,990,279, forward strand: 53,985,845–54,034,888, forward strandHOXC6: 53,990,624–54,030,823, forward strandHOXC6HOXC9: 53,994,895–54,003,337, forward strandHOXC8: 54,008,911–54,012,769, forward strandHOXC8HOXC4: 54,015,897–54,056,030, forward strandHOXC4HOXC5: 54,033,048–54,035,361, forward strandHOXC5SMUG1: 54,121,277–54,189,008, reverse strandSMUG1CBX5: 54,230,942–54,280,141, reverse strandCBX5HNRNPA1: 54,280,193–54,287,088, forward strandHNRNPA1NFE2: 54,292,107–54,301,259, reverse strandNFE2COPZ1: 54,325,131–54,351,846, forward strandCOPZ1GPR84: 54,362,445–54,364,493, reverse strandGPR84ZNF385A: 54,369,129–54,391,338, reverse strandZNF385AITGA5: 54,395,261–54,419,515, reverse strandITGA5GTSF1: 54,455,950–54,473,602, reverse strandGTSF1NCKAP1L: 54,497,713–54,548,243, forward strandNCKAP1LPDE1B: 54,549,551–54,579,241, forward strandPDE1BPPP1R1A: 54,575,387–54,588,844, reverse strandPPP1R1ALACRT: 54,630,811–54,634,895, reverse strandLACRTDCD: 54,644,589–54,648,493, reverse strandDCDMUCL1: 54,830,518–54,896,008, forward strandMUCL1Diagram of COPZ1: 9 exons on the forward strand of chromosome 12Exon 7: 1 known disease-causing siteExon 1: 54,325,131–54,325,181, 51 basesExon 2: 54,340,547–54,340,615, 69 basesExon 3: 54,342,206–54,342,287, 82 basesExon 4: 54,343,225–54,343,316, 92 basesExon 5: 54,345,460–54,345,515, 56 basesExon 6: 54,347,767–54,347,844, 78 basesExon 7: 54,348,000–54,348,051, 52 basesExon 8: 54,349,620–54,349,658, 39 basesExon 9: 54,350,476–54,351,846, 1,371 bases1246895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.9 kb of the gene's 26.7 kb; 534 of those bases code for the protein.

How a genome test reads COPZ1

1

position in COPZ1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 26.7 kb of COPZ1, introns included, not only the 1.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). COPZ1 gene: coat protein complex I subunit zeta 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/copz1

Vancouver

Dante Labs. COPZ1 gene: coat protein complex I subunit zeta 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/copz1

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