Trait
Coarse hair
Hair shafts are rough in texture.
Summary
- Also called
- Coarse hair texture, Rough hair texture
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test61 genes linked to Coarse hair
Changes in these genes cause rare conditions in which Coarse hair is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| C18orf32chromosome 18 open reading frame 32 | Always | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Always | In 1 condition |
| IFT140intraflagellar transport 140 | Always | In 1 condition |
| KRT74keratin 74 | Always | In 1 condition |
| LPAR6lysophosphatidic acid receptor 6 | Always | In 1 condition |
| NOTCH3notch receptor 3 | Always | In 1 condition |
| PLOD3procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 | Always | In 1 condition |
| PPP1CBprotein phosphatase 1 catalytic subunit beta | Always | In 1 condition |
| SEC23ASEC23 homolog A, COPII component | Always | In 2 conditions |
| SPINK5serine peptidase inhibitor Kazal type 5 | Always | In 1 condition |
| SREBF1sterol regulatory element binding transcription factor 1 | Always | In 1 condition |
| YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | Always | In 1 condition |
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Very often (80–99%) | In 2 conditions |
| ATP6V1AATPase H+ transporting V1 subunit A | Very often (80–99%) | In 1 condition |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Very often (80–99%) | In 1 condition |
| EPS8L3EPS8 signaling adaptor L3 | Very often (80–99%) | In 1 condition |
| HRHR lysine demethylase and nuclear receptor corepressor | Very often (80–99%) | In 1 condition |
| PADI3peptidyl arginine deiminase 3 | Very often (80–99%) | In 1 condition |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 2 conditions |
| TGM3transglutaminase 3 | Very often (80–99%) | In 1 condition |
| TP63tumor protein p63 | Very often (80–99%) | In 1 condition |
| AFF4ALF transcription elongation factor 4 | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| CBLCbl proto-oncogene | Often (30–79%) | In 1 condition |
| CERT1ceramide transporter 1 | Often (30–79%) | In 1 condition |
| GUSBglucuronidase beta | Often (30–79%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Often (30–79%) | In 1 condition |
| LZTR1leucine zipper like post translational regulator 1 | Often (30–79%) | In 1 condition |
| MRASmuscle RAS oncogene homolog | Often (30–79%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Often (30–79%) | In 1 condition |
| PPP1R13Lprotein phosphatase 1 regulatory subunit 13 like | Often (30–79%) | In 1 condition |
| PTENphosphatase and tensin homolog | Often (30–79%) | In 1 condition |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Often (30–79%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| RASA2RAS p21 protein activator 2 | Often (30–79%) | In 1 condition |
| RIT1Ras like without CAAX 1 | Often (30–79%) | In 1 condition |
| RRASRAS related | Often (30–79%) | In 1 condition |
| RRAS2RAS related 2 | Often (30–79%) | In 1 condition |
| SOS1SOS Ras/Rac guanine nucleotide exchange factor 1 | Often (30–79%) | In 1 condition |
| SOS2SOS Ras/Rho guanine nucleotide exchange factor 2 | Often (30–79%) | In 1 condition |
Show 21 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SPRED2sprouty related EVH1 domain containing 2 | Often (30–79%) | In 1 condition |
| SUMF1sulfatase modifying factor 1 | Often (30–79%) | In 1 condition |
| TMCO1transmembrane and coiled-coil domains 1 | Often (30–79%) | In 1 condition |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Often (30–79%) | In 1 condition |
| ATP7AATPase copper transporting alpha | Sometimes (5–29%) | In 2 conditions |
| BCKDKbranched chain keto acid dehydrogenase kinase | Sometimes (5–29%) | In 1 condition |
| EBPEBP cholestenol delta-isomerase | Sometimes (5–29%) | In 1 condition |
| HEATR3HEAT repeat containing 3 | Sometimes (5–29%) | In 1 condition |
| NOTCH2notch receptor 2 | Sometimes (5–29%) | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Sometimes (5–29%) | In 1 condition |
| BCS1LBCS1 ubiquinol-cytochrome c reductase complex chaperone | Not recorded | In 1 condition |
| CCDC47coiled-coil domain containing 47 | Not recorded | In 1 condition |
| FLNAfilamin A | Not recorded | In 1 condition |
| GNSglucosamine (N-acetyl)-6-sulfatase | Not recorded | In 1 condition |
| HGSNATheparan-alpha-glucosaminide N-acetyltransferase | Not recorded | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Not recorded | In 1 condition |
| NAGLUN-acetyl-alpha-glucosaminidase | Not recorded | In 1 condition |
| NECTIN4nectin cell adhesion molecule 4 | Not recorded | In 1 condition |
| RPS6KA3ribosomal protein S6 kinase A3 | Not recorded | In 1 condition |
| SGSHN-sulfoglucosamine sulfohydrolase | Not recorded | In 1 condition |
| SMARCAL1SNF2 related chromatin remodeling annealing helicase 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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