Trait
Intermittent involuntary muscle spasm
Clinical name: Tetany
A condition characterized by intermittent involuntary contraction of muscles (spasms) related to hypocalcemia or occasionally magnesium deficiency.
Summary
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Intermittent involuntary muscle spasm, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test23 genes linked to Intermittent involuntary muscle spasm
Changes in these genes cause rare conditions in which Intermittent involuntary muscle spasm is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GATA3GATA binding protein 3 | Always | In 1 condition |
| NEUROG3neurogenin 3 | Always | In 1 condition |
| CYP27B1cytochrome P450 family 27 subfamily B member 1 | Very often (80–99%) | In 1 condition |
| CYP2R1cytochrome P450 family 2 subfamily R member 1 | Very often (80–99%) | In 1 condition |
| ARVCFARVCF delta catenin family member | Often (30–79%) | In 1 condition |
| COMTcatechol-O-methyltransferase | Often (30–79%) | In 1 condition |
| GP1BBglycoprotein Ib platelet subunit beta | Often (30–79%) | In 1 condition |
| HIRAhistone cell cycle regulator | Often (30–79%) | In 1 condition |
| JMJD1Cjumonji domain containing 1C | Often (30–79%) | In 1 condition |
| PTHparathyroid hormone | Often (30–79%) | In 1 condition |
| RRAGDRas related GTP binding D | Often (30–79%) | In 1 condition |
| RREB1ras responsive element binding protein 1 | Often (30–79%) | In 1 condition |
| SEC24CSEC24 homolog C, COPII component | Often (30–79%) | In 1 condition |
| TBX1T-box transcription factor 1 | Often (30–79%) | In 2 conditions |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Often (30–79%) | In 1 condition |
| CASRcalcium sensing receptor | Sometimes (5–29%) | In 1 condition |
| CLDN16claudin 16 | Sometimes (5–29%) | In 1 condition |
| KCNJ1potassium inwardly rectifying channel subfamily J member 1 | Not recorded | In 1 condition |
| SLC12A1solute carrier family 12 member 1 | Not recorded | In 1 condition |
| SLC12A3solute carrier family 12 member 3 | Not recorded | In 1 condition |
| TBCEtubulin folding cofactor E | Not recorded | In 2 conditions |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Not recorded | In 1 condition |
| TRPM6transient receptor potential cation channel subfamily M member 6 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks