Trait
Elevated plasma aldosterone
Clinical name: Increased circulating aldosterone concentration
Overproduction of the mineralocorticoid aldosterone by the adrenal cortex.
Summary
- Also called
- Increased aldosterone, Increased aldosterone production, Mineralocorticoid excess
- Body system
- Abnormality of the endocrine system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Elevated plasma aldosterone, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test32 genes linked to Elevated plasma aldosterone
Changes in these genes cause rare conditions in which Elevated plasma aldosterone is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CACNA1Dcalcium voltage-gated channel subunit alpha1 D | Always | In 1 condition |
| CACNA1Hcalcium voltage-gated channel subunit alpha1 H | Always | In 1 condition |
| KCNJ1potassium inwardly rectifying channel subfamily J member 1 | Always | In 1 condition |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Always | In 2 conditions |
| SCNN1Asodium channel epithelial 1 subunit alpha | Always | In 1 condition |
| SCNN1Gsodium channel epithelial 1 subunit gamma | Always | In 1 condition |
| SLC12A1solute carrier family 12 member 1 | Always | In 1 condition |
| SLC26A3solute carrier family 26 member 3 | Always | In 1 condition |
| BSNDbarttin CLCNK type accessory subunit beta | Very often (80–99%) | In 2 conditions |
| CLCNKAchloride voltage-gated channel Ka | Very often (80–99%) | In 2 conditions |
| CLCNKBchloride voltage-gated channel Kb | Very often (80–99%) | In 3 conditions |
| KCNJ10potassium inwardly rectifying channel subfamily J member 10 | Very often (80–99%) | In 2 conditions |
| CDKN2Acyclin dependent kinase inhibitor 2A | Often (30–79%) | In 1 condition |
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| CYP11B1cytochrome P450 family 11 subfamily B member 1 | Often (30–79%) | In 2 conditions |
| CYP11B2cytochrome P450 family 11 subfamily B member 2 | Often (30–79%) | In 1 condition |
| KCNJ16potassium inwardly rectifying channel subfamily J member 16 | Often (30–79%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Often (30–79%) | In 1 condition |
| RRAGDRas related GTP binding D | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TP53tumor protein p53 | Often (30–79%) | In 1 condition |
| ZNRF3zinc and ring finger 3 | Often (30–79%) | In 1 condition |
| INSRinsulin receptor | Sometimes (5–29%) | In 1 condition |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Sometimes (5–29%) | In 1 condition |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Sometimes (5–29%) | In 1 condition |
| ARMC5armadillo repeat containing 5 | Rarely (1–4%) | In 1 condition |
| GNASGNAS complex locus | Rarely (1–4%) | In 1 condition |
| KDM1Alysine demethylase 1A | Rarely (1–4%) | In 1 condition |
| CLCN2chloride voltage-gated channel 2 | Not recorded | In 1 condition |
| CYP11A1cytochrome P450 family 11 subfamily A member 1 | Not recorded | In 1 condition |
| NR3C2nuclear receptor subfamily 3 group C member 2 | Not recorded | In 1 condition |
| SCNN1Bsodium channel epithelial 1 subunit beta | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks