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Gene

ACTN3

actinin alpha 3

Summary

Cytogenetic location
11q13.2
Coordinates
Chromosome 11: 66,546,903–66,563,334 (GRCh38)
Exons
21 exons across 16.4 kb
Protein
901 amino acids
MANE Select transcript
ENST00000513398.2NM_001104.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Trait report that reads ACTN3

How ACTN3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where ACTN3 sits. ACTN3 and 33 genes near it on chromosome 11, from 66,055,119 to 67,055,118.Chromosome 1111q13.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2566.2 Mb66.4 Mb66.6 Mb66.8 Mb67 MbSF3B2: 66,050,729–66,069,308, forward strandSF3B2PACS1: 66,070,017–66,248,638, forward strandPACS1KLC2: 66,257,267–66,267,862, forward strandKLC2RAB1B: 66,268,586–66,277,492, forward strandRAB1BCNIH2: 66,278,170–66,285,301, forward strandCNIH2YIF1A: 66,284,253–66,289,688, reverse strandYIF1ATMEM151A: 66,291,832–66,299,036, forward strandCD248: 66,314,494–66,317,044, reverse strandRIN1: 66,330,241–66,336,840, reverse strandRIN1BRMS1: 66,337,332–66,345,136, reverse strandBRMS1B4GAT1: 66,345,374–66,347,856, reverse strandB4GAT1SLC29A2: 66,360,101–66,372,476, reverse strandSLC29A2NPAS4: 66,421,033–66,426,707, forward strandNPAS4MRPL11: 66,435,075–66,466,738, reverse strandMRPL11PELI3: 66,466,303–66,478,998, forward strandPELI3DPP3: 66,479,990–66,510,188, forward strandDPP3: 66,509,079–66,533,613, forward strandBBS1: 66,510,606–66,534,660, forward strandBBS1ZDHHC24: 66,520,620–66,546,244, reverse strandZDHHC24ACTN3: 66,546,903–66,563,334, forward strandACTN3CTSF: 66,563,462–66,568,879, reverse strandCTSFCCDC87: 66,590,176–66,593,063, reverse strandCCDC87CCS: 66,592,843–66,606,703, forward strandCCSRBM14: 66,616,594–66,629,934, forward strandRBM14RBM14-RBM4: 66,616,626–66,646,469, forward strandRBM14-RBM4RBM4: 66,637,771–66,668,380, forward strandRBM4RBM4B: 66,664,994–66,677,925, reverse strandRBM4BSPTBN2: 66,682,496–66,744,670, reverse strandSPTBN2TOP6BL: 66,744,451–66,843,516, forward strandTOP6BLRCE1: 66,842,835–66,848,159, forward strandRCE1PC: 66,848,208–66,958,524, reverse strandPCLRFN4: 66,856,546–66,860,475, forward strandLRFN4C11orf86: 66,975,272–66,977,009, forward strandC11orf86SYT12: 67,006,772–67,051,110, forward strandSYT12Diagram of ACTN3: 21 exons on the forward strand of chromosome 11Exon 1: 66,546,903–66,547,084, 182 basesExon 2: 66,551,239–66,551,353, 115 basesExon 3: 66,551,528–66,551,647, 120 basesExon 4: 66,554,045–66,554,131, 87 basesExon 5: 66,554,536–66,554,623, 88 basesExon 6: 66,555,130–66,555,208, 79 basesExon 7: 66,555,286–66,555,367, 82 basesExon 8: 66,556,145–66,556,230, 86 basesExon 9: 66,557,133–66,557,225, 93 basesExon 10: 66,557,699–66,557,929, 231 basesExon 11: 66,558,027–66,558,174, 148 basesExon 12: 66,559,236–66,559,386, 151 basesExon 13: 66,559,968–66,560,076, 109 basesExon 14: 66,560,171–66,560,311, 141 basesExon 15: 66,560,573–66,560,755, 183 basesExon 16: 66,561,227–66,561,361, 135 basesExon 17: 66,561,458–66,561,637, 180 basesExon 18: 66,562,022–66,562,168, 147 basesExon 19: 66,562,257–66,562,322, 66 basesExon 20: 66,562,796–66,562,954, 159 basesExon 21: 66,563,035–66,563,334, 300 bases1215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.9 kb of the gene's 16.4 kb; 2,706 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). ACTN3 gene: actinin alpha 3. Retrieved 19 October 2026, from https://dantelabs.com/genes/actn3

Vancouver

Dante Labs. ACTN3 gene: actinin alpha 3 [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/actn3

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