Enlargement and weakening of the left ventricle not explained by coronary artery or valve disease; inherited forms involve TTN, LMNA, RBM20, FLNC, BAG3, DSP, MYH7, TNNT2, DES, PLN and many other genes, and include Barth syndrome and the Emery-Dreifuss muscular dystrophies.
What a diagnosis changes
Knowing a genetic cause supports earlier heart monitoring and family screening, and for genes with a high arrhythmia risk such as LMNA, FLNC and RBM20 it informs decisions about rhythm monitoring and implantable defibrillators.
Genes analysed
Also known as
familial dilated cardiomyopathy; idiopathic dilation cardiomyopathy
Includes 91 related subtypes ↓Hide subtypes ↑
- autosomal dominant Emery-Dreifuss muscular dystrophy
- autosomal recessive limb-girdle muscular dystrophy type 2C
- autosomal recessive limb-girdle muscular dystrophy type 2D
- autosomal recessive limb-girdle muscular dystrophy type 2E
- autosomal recessive limb-girdle muscular dystrophy type 2F
- autosomal recessive limb-girdle muscular dystrophy type 2M
- Barth syndrome
- cardiac lipidosis, familial
- cardiomyopathy, dilated, 100
- cardiomyopathy, dilated, 1LL
- cardiomyopathy, dilated, 1MM
- cardiomyopathy, dilated, 1QQ
- cardiomyopathy, dilated, 2c
- cardiomyopathy, dilated, 2D
- cardiomyopathy, dilated, 2E
- cardiomyopathy, dilated, 2F
- cardiomyopathy, dilated, 2G
- cardiomyopathy, dilated, 2H
- cardiomyopathy, dilated, 2I
- cardiomyopathy, dilated, 2j
- cardiomyopathy, dilated, 2K
- cardiomyopathy, dilated, 2l
- cardiomyopathy, dilated, 2M
- cardiomyopathy, dilated, 3C
- cirrhotic cardiomyopathy
- congenital myopathy 7A, myosin storage, autosomal dominant
- dilated cardiomyopathy 1A
- dilated cardiomyopathy 1AA
- dilated cardiomyopathy 1B
- dilated cardiomyopathy 1BB
- dilated cardiomyopathy 1C
- dilated cardiomyopathy 1CC
- dilated cardiomyopathy 1D
- dilated cardiomyopathy 1DD
- dilated cardiomyopathy 1E
- dilated cardiomyopathy 1EE
- dilated cardiomyopathy 1FF
- dilated cardiomyopathy 1G
- dilated cardiomyopathy 1GG
- dilated cardiomyopathy 1H
- dilated cardiomyopathy 1HH
- dilated cardiomyopathy 1I
- dilated cardiomyopathy 1II
- dilated cardiomyopathy 1J
- dilated cardiomyopathy 1JJ
- dilated cardiomyopathy 1K
- dilated cardiomyopathy 1KK
- dilated cardiomyopathy 1L
- dilated cardiomyopathy 1M
- dilated cardiomyopathy 1NN
- dilated cardiomyopathy 1O
- dilated cardiomyopathy 1P
- dilated cardiomyopathy 1Q
- dilated cardiomyopathy 1R
- dilated cardiomyopathy 1S
- dilated cardiomyopathy 1U
- dilated cardiomyopathy 1V
- dilated cardiomyopathy 1W
- dilated cardiomyopathy 1X
- dilated cardiomyopathy 1Y
- dilated cardiomyopathy 1Z
- dilated cardiomyopathy 2A
- dilated cardiomyopathy 2B
- dilated cardiomyopathy 3B
- DK1-congenital disorder of glycosylation
- early-onset myopathy with fatal cardiomyopathy
- Emery-Dreifuss muscular dystrophy
- Emery-Dreifuss muscular dystrophy 1, X-linked
- Emery-Dreifuss muscular dystrophy 2, autosomal dominant
- Emery-Dreifuss muscular dystrophy 3, autosomal recessive
- Emery-Dreifuss muscular dystrophy 4, autosomal dominant
- Emery-Dreifuss muscular dystrophy 5, autosomal dominant
- Emery-Dreifuss muscular dystrophy 6, X-linked
- Emery-Dreifuss muscular dystrophy 7, autosomal dominant
- familial dilated cardiomyopathy
- familial isolated dilated cardiomyopathy
- histiocytoid cardiomyopathy
- hypertrophic cardiomyopathy 25
- Kearns-Sayre syndrome
- left ventricular noncompaction 10
- left ventricular noncompaction 8
- myofibrillar myopathy 1
- non-familial dilated cardiomyopathy
- peripartum cardiomyopathy
- PGM1-congenital disorder of glycosylation
- scapuloperoneal myopathy
- symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers
- viral dilated cardiomyopathy
- X-linked Emery-Dreifuss muscular dystrophy
- X-linked myopathy with postural muscle atrophy
- X-linked scapuloperoneal muscular dystrophy
