Traits

Traits linked to APOB

apolipoprotein B

The Human Phenotype Ontology links 47 traits to APOB, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the cardiovascular system

Trait	Cât de frecvent apare
Premature hardening of arteries	Foarte des (80–99%)
Premature plaque build-up in arteries	Foarte des (80–99%)
Abnormal left ventricular function	Des (30–79%)
Angina pectoris	Des (30–79%)
Aortic atherosclerotic lesion	Des (30–79%)
Heart attack	Des (30–79%)
Heart murmur	Des (30–79%)
High blood pressure	Des (30–79%)
Myocardial steatosis	Des (30–79%)
Narrowing of kidney artery	Des (30–79%)
Peripheral arterial stenosis	Des (30–79%)
Plaque build-up in arteries supplying blood to heart	Des (30–79%)
Plaque build-up in cerebral artery	Des (30–79%)
Premature coronary artery disease	Des (30–79%)
Sudden cardiac death	Des (30–79%)
Calcification of the aorta	Uneori (5–29%)
Mitral regurgitation	Uneori (5–29%)
Supravalvular aortic stenosis	Uneori (5–29%)
Coronary artery aneurysm	Rar (1–4%)

Laboratory abnormality

Trait	Cât de frecvent apare
Decreased circulating cholesterol level	Întotdeauna
Decreased circulating high-density lipoprotein cholesterol	Întotdeauna
Decreased circulating LDL-C concentration	Întotdeauna
Elevated circulating alanine aminotransferase concentration	Întotdeauna
Elevated circulating aspartate aminotransferase concentration	Întotdeauna
Elevated lipids in blood	Întotdeauna
Elevated serum cholesterol	Întotdeauna
Increased circulating LDL level	Întotdeauna
Vitamin A deficiency	Întotdeauna
Vitamin E deficiency	Întotdeauna
Fatty infiltration of liver	Des (30–79%)

Abnormality of the eye

Trait	Cât de frecvent apare
Abnormal eye physiology	Rar (1–4%)
Damaged optic nerve	Rar (1–4%)
Corneal arcus	Neînregistrat
Retina degeneration	Neînregistrat

Abnormality of the nervous system

Trait	Cât de frecvent apare
Abnormal nervous system physiology	Rar (1–4%)
Ataxia	Neînregistrat
Diminished deep tendon reflex	Neînregistrat

Abnormality of head or neck

Trait	Cât de frecvent apare
Abnormal internal carotid artery morphology	Des (30–79%)
Fatty deposits in skin around the eyes	Neînregistrat

Abnormality of the integument

Trait	Cât de frecvent apare
Tendon xanthomatosis	Uneori (5–29%)
Yellow bumps of fatty deposits on skin	Uneori (5–29%)

Abnormality of blood and blood-forming tissues

Trait	Cât de frecvent apare
Acanthocytosis	Întotdeauna

Abnormality of the digestive system

Trait	Cât de frecvent apare
Fat in feces	Întotdeauna

Abnormality of the genitourinary system

Trait	Cât de frecvent apare
Fatty kidney	Uneori (5–29%)

Abnormality of the musculoskeletal system

Trait	Cât de frecvent apare
Abnormal shape of tendon	Des (30–79%)

Abnormality of the respiratory system

Trait	Cât de frecvent apare
Breathing difficulty	Des (30–79%)

Constitutional symptom

Trait	Cât de frecvent apare
Joint pain	Uneori (5–29%)

Cât de frecvent apare în rândul persoanelor cu una dintre afecțiunile asociate genei, cel mai des întâlnit dintre acestea, conform Human Phenotype Ontology. Aceste pagini descriu trăsături și cercetările din spatele lor; ele nu reprezintă un diagnostic, iar pentru simptome trebuie să vă adresați medicului sau consilierului genetic.

De unde provin aceste informații

The Human Phenotype Ontology, release 2026-09-01: the traits linked to APOB and how often each is seen. Find out more at hpo.jax.org.

Un test. Răspunsuri pentru o viață.

De la 449 $Livrare gratuită · Rezultate în 6–8 săptămâni

Comandați Genome Test-ul meu