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Trait

B-cell lymphoma

A type of lymphoma that originates in B-cells.

HPO HP:0012191

Summary

Also called
B cell lymphoma
Body system
Abnormality of blood and blood-forming tissuesAbnormal tissue mass

24 genes linked to B-cell lymphoma

Changes in these genes cause rare conditions in which B-cell lymphoma is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
ITPR3inositol 1,4,5-trisphosphate receptor type 3AlwaysIn 1 condition
MAGT1magnesium transporter 1AlwaysIn 1 condition
NFATC2nuclear factor of activated T cells 2AlwaysIn 1 condition
PTPRCprotein tyrosine phosphatase receptor type CAlwaysIn 1 condition
RASGRP1RAS guanyl releasing protein 1AlwaysIn 1 condition
ATMATM serine/threonine kinaseVery often (80–99%)In 1 condition
BCL10BCL10 immune signaling adaptorVery often (80–99%)In 1 condition
BIRC3baculoviral IAP repeat containing 3Very often (80–99%)In 1 condition
CCND1cyclin D1Very often (80–99%)In 1 condition
FOXP1forkhead box P1Very often (80–99%)In 1 condition
IGHimmunoglobulin heavy locusVery often (80–99%)In 2 conditions
MALT1MALT1 paracaspaseVery often (80–99%)In 1 condition
IKZF3IKAROS family zinc finger 3Often (30–79%)In 1 condition
ITKIL2 inducible T cell kinaseOften (30–79%)In 1 condition
SYKspleen associated tyrosine kinaseOften (30–79%)In 1 condition
CASP10caspase 10Sometimes (5–29%)In 1 condition
DIAPH1diaphanous related formin 1Sometimes (5–29%)In 1 condition
FASFas cell surface death receptorSometimes (5–29%)In 1 condition
FASLGFas ligandSometimes (5–29%)In 1 condition
FCHO1FCH and mu domain containing endocytic adaptor 1Sometimes (5–29%)In 1 condition
NBNnibrinSometimes (5–29%)In 1 condition
STAT6signal transducer and activator of transcription 6Sometimes (5–29%)In 1 condition
PIK3R1phosphoinositide-3-kinase regulatory subunit 1Rarely (1–4%)In 1 condition
ADAadenosine deaminaseNot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Non-Hodgkin lymphoma

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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