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Gene

SARDH

sarcosine dehydrogenase

Summary

Cytogenetic location
9q34.2
Coordinates
Chromosome 9: 133,663,560–133,738,352 (GRCh38)
Exons
21 exons across 74.8 kb
Protein
918 amino acids
Also known as
SDH
Previous symbols
DMGDHL1
MANE Select transcript
ENST00000439388.6NM_001134707.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SARDH yet. The test sequences your whole genome, so your data includes it all the same.

How SARDH is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where SARDH sits. SARDH and 21 genes near it on chromosome 9, from 133,200,956 to 134,200,955.Chromosome 99q34.2p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.3133.4 Mb133.6 Mb133.8 Mb134 Mb134.2 MbOBP2B: 133,205,277–133,209,309, reverse strandOBP2BABO: 133,233,278–133,276,024, reverse strandABOSURF6: 133,328,684–133,336,289, reverse strandMED22: 133,338,312–133,348,140, reverse strandRPL7A: 133,347,950–133,351,435, forward strandSURF1: 133,351,069–133,356,676, reverse strandSURF1SURF2: 133,356,520–133,362,917, forward strandSURF2SURF4: 133,361,450–133,376,233, reverse strandSURF4STKLD1: 133,376,332–133,406,096, forward strandSTKLD1REXO4: 133,406,026–133,418,096, reverse strandREXO4ADAMTS13: 133,414,358–133,459,402, forward strandADAMTS13CACFD1: 133,459,965–133,470,848, forward strandCACFD1SLC2A6: 133,462,053–133,479,148, reverse strandSLC2A6MYMK: 133,514,586–133,528,612, reverse strandMYMKADAMTSL2: 133,532,164–133,575,522, forward strandADAMTSL2FAM163B: 133,577,076–133,609,420, reverse strandFAM163BDBH: 133,634,456–133,659,329, forward strandDBHSARDH: 133,663,560–133,738,352, reverse strandSARDHVAV2: 133,761,892–133,992,854, reverse strandVAV2BRD3OS: 134,025,429–134,034,666, forward strandBRD3OSBRD3: 134,030,305–134,068,560, reverse strandBRD3WDR5: 134,134,346–134,159,971, forward strandWDR5Diagram of SARDH: 21 exons on the reverse strand of chromosome 9Exon 10: 1 known disease-causing siteExon 21: 133,663,560–133,664,014, 455 basesExon 20: 133,666,735–133,666,870, 136 basesExon 19: 133,670,584–133,670,752, 169 basesExon 18: 133,671,535–133,671,697, 163 basesExon 17: 133,685,193–133,685,286, 94 basesExon 16: 133,690,380–133,690,527, 148 basesExon 15: 133,694,258–133,694,371, 114 basesExon 14: 133,696,223–133,696,361, 139 basesExon 13: 133,702,916–133,703,029, 114 basesExon 12: 133,704,948–133,705,031, 84 basesExon 11: 133,708,287–133,708,428, 142 basesExon 10: 133,712,619–133,712,709, 91 basesExon 9: 133,713,038–133,713,124, 87 basesExon 8: 133,717,326–133,717,455, 130 basesExon 7: 133,718,938–133,719,042, 105 basesExon 6: 133,729,765–133,729,865, 101 basesExon 5: 133,730,064–133,730,187, 124 basesExon 4: 133,731,305–133,731,484, 180 basesExon 3: 133,732,423–133,732,601, 179 basesExon 2: 133,733,843–133,734,203, 361 basesExon 1: 133,738,254–133,738,352, 99 bases21201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 74.8 kb; 2,757 of those bases code for the protein.

How a genome test reads SARDH

1

position in SARDH where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 74.8 kb of SARDH, introns included, not only the 3.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SARDH gene: sarcosine dehydrogenase. Retrieved 17 October 2026, from https://dantelabs.com/genes/sardh

Vancouver

Dante Labs. SARDH gene: sarcosine dehydrogenase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sardh

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