Trait
Raynaud phenomenon
Summary
- Also called
- Raynaud's phenomenon
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
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Get my Genome Test60 genes linked to Raynaud phenomenon
Changes in these genes cause rare conditions in which Raynaud phenomenon is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FEM1Bfem-1 homolog B | Always | In 1 condition |
| FLNAfilamin A | Always | In 1 condition |
| LBRlamin B receptor | Always | In 1 condition |
| STING1stimulator of interferon response cGAMP interactor 1 | Always | In 1 condition |
| TREX1three prime repair exonuclease 1 | Very often (80–99%) | In 5 conditions |
| ADA2adenosine deaminase 2 | Often (30–79%) | In 2 conditions |
| APOLD1apolipoprotein L domain containing 1 | Often (30–79%) | In 1 condition |
| BANK1B cell scaffold protein with ankyrin repeats 1 | Often (30–79%) | In 1 condition |
| BLKBLK proto-oncogene, Src family tyrosine kinase | Often (30–79%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Often (30–79%) | In 1 condition |
| C4Bcomplement C4B (Chido/Rodgers blood group) | Often (30–79%) | In 1 condition |
| COL4A1collagen type IV alpha 1 chain | Often (30–79%) | In 2 conditions |
| COQ2coenzyme Q2, polyprenyltransferase | Often (30–79%) | In 2 conditions |
| CR2complement C3d receptor 2 | Often (30–79%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Often (30–79%) | In 1 condition |
| DNASE1deoxyribonuclease 1 | Often (30–79%) | In 2 conditions |
| ETS1ETS proto-oncogene 1, transcription factor | Often (30–79%) | In 1 condition |
| FCGR2BFc gamma receptor IIb | Often (30–79%) | In 2 conditions |
| FCGR3BFc gamma receptor IIIb | Often (30–79%) | In 1 condition |
| FLT3LGfms related receptor tyrosine kinase 3 ligand | Often (30–79%) | In 1 condition |
| GUCY1A1guanylate cyclase 1 soluble subunit alpha 1 | Often (30–79%) | In 2 conditions |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Often (30–79%) | In 1 condition |
| IGHG1immunoglobulin heavy constant gamma 1 (G1m marker) | Often (30–79%) | In 1 condition |
| IL10interleukin 10 | Often (30–79%) | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Often (30–79%) | In 2 conditions |
| IRF5interferon regulatory factor 5 | Often (30–79%) | In 1 condition |
| ITGAMintegrin subunit alpha M | Often (30–79%) | In 1 condition |
| JAZF1JAZF zinc finger 1 | Often (30–79%) | In 1 condition |
| KIAA0319LKIAA0319 like | Often (30–79%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Often (30–79%) | In 1 condition |
| PDCD1programmed cell death 1 | Often (30–79%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 1 condition |
| PXKPX domain containing serine/threonine kinase like | Often (30–79%) | In 1 condition |
| RNF125ring finger protein 125 | Often (30–79%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Often (30–79%) | In 2 conditions |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 2 conditions |
| TLR7toll like receptor 7 | Often (30–79%) | In 2 conditions |
| TNFAIP3TNF alpha induced protein 3 | Often (30–79%) | In 1 condition |
| TNFSF4TNF superfamily member 4 | Often (30–79%) | In 1 condition |
| TNIP1TNFAIP3 interacting protein 1 | Often (30–79%) | In 1 condition |
Show 20 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| UBE2L3ubiquitin conjugating enzyme E2 L3 | Often (30–79%) | In 1 condition |
| ACP5acid phosphatase 5, tartrate resistant | Sometimes (5–29%) | In 2 conditions |
| ADARadenosine deaminase RNA specific | Sometimes (5–29%) | In 1 condition |
| FCGR2AFc gamma receptor IIa | Sometimes (5–29%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Sometimes (5–29%) | In 1 condition |
| LSM11LSM11, U7 small nuclear RNA associated | Sometimes (5–29%) | In 1 condition |
| NOTCH3notch receptor 3 | Sometimes (5–29%) | In 1 condition |
| RNASEH2Aribonuclease H2 subunit A | Sometimes (5–29%) | In 1 condition |
| RNASEH2Bribonuclease H2 subunit B | Sometimes (5–29%) | In 1 condition |
| RNASEH2Cribonuclease H2 subunit C | Sometimes (5–29%) | In 1 condition |
| RNU7-1RNA, U7 small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Sometimes (5–29%) | In 1 condition |
| SEC61A1SEC61 translocon subunit alpha 1 | Sometimes (5–29%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Sometimes (5–29%) | In 1 condition |
| CLCNKBchloride voltage-gated channel Kb | Rarely (1–4%) | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Rarely (1–4%) | In 1 condition |
| SAT1spermidine/spermine N1-acetyltransferase 1 | Rarely (1–4%) | In 1 condition |
| SLC12A3solute carrier family 12 member 3 | Rarely (1–4%) | In 1 condition |
| AGXTalanine--glyoxylate aminotransferase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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