Gene
ZNHIT3
zinc finger HIT-type containing 3
- HGNC 12309↗(opens in a new tab)
- Ensembl gene ENSG00000273611↗(opens in a new tab)
- NCBI Gene 9326↗(opens in a new tab)
Summary
- Cytogenetic location
- 17q12
- Coordinates
- Chromosome 17: 36,486,681–36,495,822 (GRCh38)
- Exons
- 5 exons across 9.1 kb
- Protein
- 155 amino acids
- Also known as
- Hit1
- Previous symbols
- TRIP3
- MANE Select transcript
- ENST00000617429.5NM_004773.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads ZNHIT3 yet. The test sequences your whole genome, so your data includes it all the same.
How ZNHIT3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 0.9 kb of the gene's 9.1 kb; 468 of those bases code for the protein.
How a genome test reads ZNHIT3
3
positions in ZNHIT3 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 9.1 kb of ZNHIT3, introns included, not only the 0.9 kb of exons.
Traits linked to ZNHIT3
The Human Phenotype Ontology lists these as features of the rare conditions ZNHIT3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormality of movement
- Decrease in size of the outer layer of the brain due to loss of brain cells
- Drowsiness
- EEG abnormality
- Epilepsy
- Global developmental delay
- Hypsarrhythmia
- Increased reflexes
Show 16 more traits
- Infantile spasms
- Intellectual disability, severe
- Atrophy/Degeneration affecting the brainstem
- Cavity within brain
- Degeneration of cerebellum
- Too much cerebrospinal fluid in the brain
- Ventriculomegaly
- Developmental stagnation
- Fewer and broader ridges in brain
- Infantile encephalopathy
- IQ less than 20
- Jerking
- Loss of brain cells
- More grooves in brain
- Peripheral dysmyelination
- Underdevelopment of part of brain called corpus callosum
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). ZNHIT3 gene: zinc finger HIT-type containing 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/znhit3
Dante Labs. ZNHIT3 gene: zinc finger HIT-type containing 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/znhit3
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