Skip to content
Use your HSA or FSA funds

Gene

SC5D

sterol-C5-desaturase

Summary

Cytogenetic location
11q23.3-q24.1
Coordinates
Chromosome 11: 121,292,771–121,313,410 (GRCh38)
Exons
5 exons across 20.6 kb
Protein
299 amino acids
Previous symbols
SC5DL
MANE Select transcript
ENST00000264027.9NM_006918.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SC5D yet. The test sequences your whole genome, so your data includes it all the same.

How SC5D is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where SC5D sits. SC5D and 5 genes near it on chromosome 11, from 120,803,091 to 121,803,090.Chromosome 1111q23.3-q24.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25121 Mb121.2 Mb121.4 Mb121.6 Mb121.8 MbGRIK4: 120,511,709–120,988,906, forward strandGRIK4TBCEL: 121,024,070–121,092,082, forward strandTBCELTBCEL-TECTA: 121,024,125–121,113,108, forward strandTBCEL-TECTATECTA: 121,101,243–121,191,490, forward strandTECTASC5D: 121,292,771–121,313,410, forward strandSC5DSORL1: 121,451,581–121,633,763, forward strandSORL1Diagram of SC5D: 5 exons on the forward strand of chromosome 11Exon 2: 1 known disease-causing siteExon 3: 2 known disease-causing sitesExon 5: 1 known disease-causing siteExon 1: 121,292,771–121,292,816, 46 basesExon 2: 121,303,366–121,303,585, 220 basesExon 3: 121,304,361–121,304,493, 133 basesExon 4: 121,306,386–121,306,486, 101 basesExon 5: 121,307,057–121,313,410, 6,354 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.9 kb of the gene's 20.6 kb; 900 of those bases code for the protein.

How a genome test reads SC5D

4

positions in SC5D where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 20.6 kb of SC5D, introns included, not only the 6.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SC5D gene: sterol-C5-desaturase. Retrieved 17 October 2026, from https://dantelabs.com/genes/sc5d

Vancouver

Dante Labs. SC5D gene: sterol-C5-desaturase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sc5d

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test