Gene
CBY1
chibby 1, beta catenin antagonist
- HGNC 1307↗(opens in a new tab)
- Ensembl gene ENSG00000100211↗(opens in a new tab)
- NCBI Gene 25776↗(opens in a new tab)
Summary
- Cytogenetic location
- 22q13.1
- Coordinates
- Chromosome 22: 38,656,638–38,673,850 (GRCh38)
- Exons
- 5 exons across 17.2 kb
- Protein
- 126 amino acids
- Also known as
- PIGEA14, PIGEA-14, Chibby, Cby, Chibby1
- Previous symbols
- C22orf2, PGEA1
- MANE Select transcript
- ENST00000216029.8NM_015373.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How CBY1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.1 kb of the gene's 17.2 kb; 381 of those bases code for the protein.
Traits linked to CBY1
The Human Phenotype Ontology lists these as features of the rare conditions CBY1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Ataxia
- Cerebellar vermis hypoplasia
- Global developmental delay
- Intellectual disability
- Abnormal gait
- Abnormality of neuronal migration
- Aplasia/Hypoplasia of the corpus callosum
- Epilepsy
Show 3 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). CBY1 gene: chibby 1, beta catenin antagonist. Retrieved 17 October 2026, from https://dantelabs.com/genes/cby1
Dante Labs. CBY1 gene: chibby 1, beta catenin antagonist [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cby1
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