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Trait

Opsoclonus

Bursts of large-amplitude multidirectional saccades without intersaccadic interval

HPO HP:0010543

Summary

Body system
Abnormality of the eye

10 condition reports read genes linked to this trait

Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.

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15 genes linked to Opsoclonus

Changes in these genes cause rare conditions in which Opsoclonus is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
CLCN7Cl-/H+ antiporter 7Very often (80–99%)In 1 condition
OSTM1osteoclastogenesis associated transmembrane protein 1Very often (80–99%)In 1 condition
SNX10sorting nexin 10Very often (80–99%)In 1 condition
TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3Very often (80–99%)In 1 condition
TNFSF11TNF superfamily member 11Very often (80–99%)In 1 condition
FRMD5FERM domain containing 5Often (30–79%)In 1 condition
TMEM240transmembrane protein 240Sometimes (5–29%)In 1 condition
ALKALK receptor tyrosine kinaseRarely (1–4%)In 1 condition
GBA1glucosylceramidase beta 1Rarely (1–4%)In 1 condition
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1Rarely (1–4%)In 1 condition
LIN28Blin-28 RNA binding posttranscriptional regulator BRarely (1–4%)In 1 condition
LMO1LIM domain only 1Rarely (1–4%)In 1 condition
MYCNMYCN proto-oncogene, bHLH transcription factorRarely (1–4%)In 1 condition
PHOX2Bpaired like homeobox 2BRarely (1–4%)In 1 condition
KIF1Bkinesin family member 1BNot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal involuntary eye movementsSaccadic oscillation

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.18-e609d43e.

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