Trait

Wide nasal base

Increased distance between the attachments of the alae nasi to the face.

Also called: Broad base of nose, Broad nasal base, Increased width of base of nose, Increased width of nasal base, Wide base of nose
Body system: Abnormality of head or neck

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/wide-nasal-base.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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29 genes linked to Wide nasal base

Changes in these genes cause rare conditions in which Wide nasal base is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ATP6V1E1ATPase H+ transporting V1 subunit E1	Always	In 1 condition
EXOSC2exosome component 2	Always	In 1 condition
FLNAfilamin A	Always	In 1 condition
LIFRLIF receptor subunit alpha	Always	In 1 condition
MYCNMYCN proto-oncogene, bHLH transcription factor	Always	In 1 condition
MYT1Lmyelin transcription factor 1 like	Always	In 1 condition
ATP6V1B2ATPase H+ transporting V1 subunit B2	Very often (80–99%)	In 1 condition
TBC1D24TBC1 domain family member 24	Very often (80–99%)	In 1 condition
ARID1AAT-rich interaction domain 1A	Often (30–79%)	In 1 condition
ARID1BAT-rich interaction domain 1B	Often (30–79%)	In 1 condition
ARID2AT-rich interaction domain 2	Often (30–79%)	In 1 condition
DPF2double PHD fingers 2	Often (30–79%)	In 1 condition
SMARCA4SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4	Often (30–79%)	In 1 condition
SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1	Often (30–79%)	In 1 condition
SMARCC2SWI/SNF related BAF chromatin remodeling complex subunit C2	Often (30–79%)	In 1 condition
SMARCD1SWI/SNF related BAF chromatin remodeling complex subunit D1	Often (30–79%)	In 1 condition
SMARCE1SWI/SNF related BAF chromatin remodeling complex subunit E1	Often (30–79%)	In 1 condition
SOX11SRY-box transcription factor 11	Often (30–79%)	In 1 condition
SOX4SRY-box transcription factor 4	Often (30–79%)	In 1 condition
ABCA5ATP binding cassette subfamily A member 5	Sometimes (5–29%)	In 1 condition
ATXN7L3ataxin 7 like 3	Sometimes (5–29%)	In 1 condition
BCORL1BCL6 corepressor like 1	Sometimes (5–29%)	In 1 condition
KMT5Blysine methyltransferase 5B	Sometimes (5–29%)	In 1 condition
SIN3ASIN3 transcription regulator family member A	Sometimes (5–29%)	In 1 condition
SLC26A2solute carrier family 26 member 2	Sometimes (5–29%)	In 1 condition
SNX14sorting nexin 14	Sometimes (5–29%)	In 2 conditions
USP9Xubiquitin specific peptidase 9 X-linked	Sometimes (5–29%)	In 1 condition
CTCFCCCTC-binding factor	Rarely (1–4%)	In 1 condition
SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal nasal base

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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