Trait
Kidney inflammation
Clinical name: Nephritis
The presence of inflammation affecting the kidney.
Summary
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test24 genes linked to Kidney inflammation
Changes in these genes cause rare conditions in which Kidney inflammation is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| HMOX1heme oxygenase 1 | Always | In 2 conditions |
| PLD4phospholipase D family member 4 | Always | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Often (30–79%) | In 1 condition |
| MYH9myosin heavy chain 9 | Often (30–79%) | In 1 condition |
| SAT1spermidine/spermine N1-acetyltransferase 1 | Often (30–79%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Often (30–79%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 1 condition |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Often (30–79%) | In 1 condition |
| AIREautoimmune regulator | Sometimes (5–29%) | In 1 condition |
| LMX1BLIM homeobox transcription factor 1 beta | Sometimes (5–29%) | In 1 condition |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Sometimes (5–29%) | In 1 condition |
| PLGplasminogen | Sometimes (5–29%) | In 1 condition |
| XIAPX-linked inhibitor of apoptosis | Sometimes (5–29%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Not recorded | In 1 condition |
| CASP10caspase 10 | Not recorded | In 1 condition |
| CD151CD151 molecule (Raph blood group) | Not recorded | In 1 condition |
| COL4A3collagen type IV alpha 3 chain | Not recorded | In 2 conditions |
| COL4A4collagen type IV alpha 4 chain | Not recorded | In 2 conditions |
| COL4A5collagen type IV alpha 5 chain | Not recorded | In 1 condition |
| DNASE1deoxyribonuclease 1 | Not recorded | In 1 condition |
| FCGR2AFc gamma receptor IIa | Not recorded | In 1 condition |
| FCGR2BFc gamma receptor IIb | Not recorded | In 1 condition |
| TREX1three prime repair exonuclease 1 | Not recorded | In 1 condition |
| UMODuromodulin | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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