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Trait
Decrease in blood pressure upon standing up
Clinical name: Orthostatic hypotension
A form of hypotension characterized by a sudden fall in blood pressure that occurs when a person assumes a standing position.
Summary
- Also called
- Postural hypotension
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Get my Genome Test47 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Hereditary Pheochromocytoma and ParagangliomaReads 9 of these genesMAXRETSDHASDHAF2SDHBSDHCAbout this report →
- Urinary and Renal System TumourReads 5 of these genesRETSDHASDHAF2SDHBVHLAbout this report →
- Malignant Endocrine NeoplasmReads 4 of these genesRETSDHASDHAF2SDHBAbout this report →
- Hereditary Gastrointestinal Stromal TumourReads 2 of these genesSDHBSDHCAbout this report →
Show 43 more reports
- Alacrima, Achalasia and Intellectual Disability Syndrome (GMPPA)Reads 1 of these genesGMPPAAbout this report →
- Caffey DiseaseReads 1 of these genesCOL1A1About this report →
- Hereditary Leiomyomatosis and Renal Cell CancerReads 1 of these genesFHAbout this report →
- Primary Microcephaly 26 (LMNB1)Reads 1 of these genesLMNB1About this report →
- Von Hippel-Lindau DiseaseReads 1 of these genesVHLAbout this report →
- PolycythemiaReads 2 of these genesEPAS1VHLAbout this report →
- Sandhoff Disease and GM2 Activator DeficiencyReads 1 of these genesHEXBAbout this report →
- Kidney CancerReads 2 of these genesSDHBVHLAbout this report →
- Ehlers-Danlos SyndromeReads 3 of these genesCOL1A1COL5A1COL5A2About this report →
- Hereditary AmyloidosisReads 2 of these genesB2MGSNAbout this report →
- Disorder of Copper MetabolismReads 1 of these genesATP7AAbout this report →
- Hirschsprung Disease & Related Enteric NeurocristopathiesReads 1 of these genesRETAbout this report →
- MedulloblastomaReads 1 of these genesELP1About this report →
- Rare Hereditary Peripheral NeuropathiesReads 8 of these genesELP1FHGSNSDHASPG11ATP7AAbout this report →
- Parkinson DiseaseReads 2 of these genesCHCHD2SNCAAbout this report →
- Adult-Onset Leukodystrophies (CSF1R, LMNB1, Nasu-Hakola)Reads 1 of these genesLMNB1About this report →
- NeurofibromatosisReads 1 of these genesNF1About this report →
- Overgrowth Syndromes (Sotos, Weaver, Tatton-Brown-Rahman, Malan)Reads 1 of these genesDNMT3AAbout this report →
- Heritable Pulmonary Arterial Hypertension (HPAH)Reads 1 of these genesCAV1About this report →
- Alpha-Mannosidosis and Other GlycoproteinosesReads 1 of these genesCTSAAbout this report →
- Familial Glucocorticoid DeficiencyReads 1 of these genesAAASAbout this report →
- Mendelian Susceptibility to Mycobacterial Disease (MSMD)Reads 1 of these genesIL12RB1About this report →
- BH4 Deficiency & Monoamine Neurotransmitter DisordersReads 1 of these genesDBHAbout this report →
- LipodystrophyReads 1 of these genesCAV1About this report →
- Lysosomal Storage DiseaseReads 2 of these genesCTSAHEXBAbout this report →
- Inherited Neurodegenerative DisordersReads 5 of these genesSDHALMNB1SPG11ATP7AHEXBAbout this report →
- Glycogen Storage DiseaseReads 1 of these genesGBE1About this report →
- Monogenic Hypertension & Mineralocorticoid DisordersReads 1 of these genesCYP11B2About this report →
- Cutis LaxaReads 1 of these genesATP7AAbout this report →
- Hereditary Corneal DystrophiesReads 1 of these genesGSNAbout this report →
- Charcot-Marie-Tooth DiseaseReads 2 of these genesSPG11ATP7AAbout this report →
- Hereditary Sensory and Autonomic Neuropathies (incl. Familial Dysautonomia)Reads 1 of these genesELP1About this report →
- Spinal Muscular AtrophyReads 1 of these genesATP7AAbout this report →
- Amyotrophic Lateral Sclerosis (ALS)Reads 1 of these genesSPG11About this report →
- Thyroid CancerReads 1 of these genesRETAbout this report →
- Limb-Girdle Muscular DystrophyReads 1 of these genesTNPO3About this report →
- Osteogenesis ImperfectaReads 1 of these genesCOL1A1About this report →
- Hereditary Spastic ParaplegiaReads 1 of these genesSPG11About this report →
- Leigh SyndromeReads 1 of these genesSDHAAbout this report →
- Other Inherited LeukodystrophiesReads 1 of these genesLMNB1About this report →
- Primary Mitochondrial DiseaseReads 1 of these genesCOQ2About this report →
- Epilepsy (Full Panel)Reads 1 of these genesMDH2About this report →
- Other Inborn Errors of ImmunityReads 1 of these genesB2MAbout this report →
Read the genes linked to Decrease in blood pressure upon standing up, and the rest of your genome, with one test.
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Get my Genome Test49 genes linked to Decrease in blood pressure upon standing up
Changes in these genes cause rare conditions in which Decrease in blood pressure upon standing up is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| B2Mbeta-2-microglobulin | Always | In 1 condition |
| CTSAcathepsin A | Always | In 1 condition |
| CYB561cytochrome b561 | Always | In 1 condition |
| DBHdopamine beta-hydroxylase | Always | In 2 conditions |
| RAB3ARAB3A, member RAS oncogene family | Always | In 1 condition |
| ELP1elongator acetyltransferase complex subunit 1 | Very often (80–99%) | In 2 conditions |
| CAV1caveolin 1 | Often (30–79%) | In 1 condition |
| CYP11B2cytochrome P450 family 11 subfamily B member 2 | Often (30–79%) | In 2 conditions |
| DLSTdihydrolipoamide S-succinyltransferase | Often (30–79%) | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Often (30–79%) | In 1 condition |
| EPAS1endothelial PAS domain protein 1 | Often (30–79%) | In 1 condition |
| FHfumarate hydratase | Often (30–79%) | In 1 condition |
| GSNgelsolin | Often (30–79%) | In 1 condition |
| IL12Ainterleukin 12A | Often (30–79%) | In 1 condition |
| IL12RB1interleukin 12 receptor subunit beta 1 | Often (30–79%) | In 1 condition |
| IRF5interferon regulatory factor 5 | Often (30–79%) | In 1 condition |
| KIF1Bkinesin family member 1B | Often (30–79%) | In 1 condition |
| MAXMYC associated transcriptional regulator X | Often (30–79%) | In 1 condition |
| MDH2malate dehydrogenase 2 | Often (30–79%) | In 1 condition |
| MMEL1membrane metalloendopeptidase like 1 | Often (30–79%) | In 1 condition |
| NF1neurofibromin 1 | Often (30–79%) | In 1 condition |
| POU2AF1POU class 2 homeobox associating factor 1 | Often (30–79%) | In 1 condition |
| RETret proto-oncogene | Often (30–79%) | In 2 conditions |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Often (30–79%) | In 1 condition |
| SDHAF2succinate dehydrogenase complex assembly factor 2 | Often (30–79%) | In 1 condition |
| SDHBsuccinate dehydrogenase complex iron sulfur subunit B | Often (30–79%) | In 2 conditions |
| SDHCsuccinate dehydrogenase complex subunit C | Often (30–79%) | In 1 condition |
| SDHDsuccinate dehydrogenase complex subunit D | Often (30–79%) | In 2 conditions |
| SLC25A11solute carrier family 25 member 11 | Often (30–79%) | In 1 condition |
| SPIBSpi-B transcription factor | Often (30–79%) | In 1 condition |
| TMEM127transmembrane protein 127 | Often (30–79%) | In 1 condition |
| TNFSF15TNF superfamily member 15 | Often (30–79%) | In 1 condition |
| TNPO3transportin 3 | Often (30–79%) | In 1 condition |
| VHLvon Hippel-Lindau tumor suppressor | Often (30–79%) | In 2 conditions |
| CHCHD2coiled-coil-helix-coiled-coil-helix domain containing 2 | Sometimes (5–29%) | In 1 condition |
| CHRNA3cholinergic receptor nicotinic alpha 3 subunit | Sometimes (5–29%) | In 1 condition |
| GBE11,4-alpha-glucan branching enzyme 1 | Sometimes (5–29%) | In 1 condition |
| GMPPAGDP-mannose pyrophosphorylase A | Sometimes (5–29%) | In 1 condition |
| LMNB1lamin B1 | Sometimes (5–29%) | In 1 condition |
| SAA1serum amyloid A1 | Sometimes (5–29%) | In 1 condition |
Show 9 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SPG11SPG11 vesicle trafficking associated, spatacsin | Sometimes (5–29%) | In 1 condition |
| COL1A1collagen type I alpha 1 chain | Rarely (1–4%) | In 1 condition |
| COL5A1collagen type V alpha 1 chain | Rarely (1–4%) | In 1 condition |
| COL5A2collagen type V alpha 2 chain | Rarely (1–4%) | In 1 condition |
| AAASaladin WD repeat nucleoporin | Not recorded | In 1 condition |
| ATP7AATPase copper transporting alpha | Not recorded | In 1 condition |
| COQ2coenzyme Q2, polyprenyltransferase | Not recorded | In 1 condition |
| HEXBhexosaminidase subunit beta | Not recorded | In 1 condition |
| SNCAsynuclein alpha | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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