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Gene

NKX1-1

NK1 homeobox 1

Summary

Cytogenetic location
4p16.3
Coordinates
Chromosome 4: 1,402,932–1,406,442 (GRCh38)
Exons
2 exons across 3.5 kb
Protein
448 amino acids
Also known as
HSPX153, SAX2
MANE Select transcript
ENST00000422806.2NM_001290079.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads NKX1-1 yet. The test sequences your whole genome, so your data includes it all the same.

How NKX1-1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 4, with a bracket where NKX1-1 sits. NKX1-1 and 18 genes near it on chromosome 4, from 904,687 to 1,904,686.Chromosome 44p16.3p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.21 Mb1.2 Mb1.4 Mb1.6 Mb1.8 MbGAK: 849,275–932,411, reverse strandGAKTMEM175: 932,153–958,989, forward strandTMEM175DGKQ: 958,884–986,895, reverse strandDGKQSLC26A1: 978,992–997,659, reverse strandSLC26A1IDUA: 986,997–1,008,344, forward strandIDUAFGFRL1: 1,008,649–1,026,901, forward strandFGFRL1RNF212: 1,056,247–1,113,697, reverse strandRNF212SPON2: 1,166,928–1,208,962, reverse strandSPON2CTBP1: 1,211,434–1,250,333, reverse strandCTBP1MAEA: 1,289,839–1,340,148, forward strandMAEAUVSSA: 1,345,691–1,395,989, forward strandUVSSANKX1-1: 1,402,932–1,406,442, reverse strandNKX1-1FAM53A: 1,617,915–1,684,356, reverse strandFAM53ASLBP: 1,692,731–1,712,344, reverse strandSLBPTACC3: 1,712,858–1,745,178, forward strandTACC3TMEM129: 1,715,951–1,721,367, reverse strandTMEM129FGFR3: 1,793,286–1,808,873, forward strandFGFR3LETM1: 1,811,479–1,856,244, reverse strandLETM1NSD2: 1,870,559–1,982,207, forward strandNSD2Diagram of NKX1-1: 2 exons on the reverse strand of chromosome 4Exon 2: 1,402,932–1,403,815, 884 basesExon 1: 1,405,980–1,406,442, 463 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 3.5 kb; 1,347 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). NKX1-1 gene: NK1 homeobox 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/nkx1-1

Vancouver

Dante Labs. NKX1-1 gene: NK1 homeobox 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nkx1-1

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