Trait
Uncontrollable movement in upper arms
Clinical name: Upper limb spasticity
Summary
- Also called
- Spastic upper extremities, Spastic upper extremity, Spastic upper limb, Spastic upper limbs, Spasticity in upper extremities, Spasticity in upper extremity, Spasticity in upper limb, Spasticity in upper limbs, Spasticity of upper extremities, Spasticity of upper extremity, Spasticity of upper limb, Spasticity of upper limbs, Upper extremities spasticity, Upper extremity spasticity
Reference genomeGRCh38hg38
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Get my Genome Test40 genes linked to Uncontrollable movement in upper arms
Changes in these genes cause rare conditions in which Uncontrollable movement in upper arms is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GBA2glucosylceramidase beta 2 | Always | In 2 conditions |
| GJC2gap junction protein gamma 2 | Always | In 1 condition |
| GPRC5BG protein-coupled receptor class C group 5 member B | Always | In 1 condition |
| PGBD5piggyBac transposable element derived 5 | Always | In 1 condition |
| ALS2alsin Rho guanine nucleotide exchange factor ALS2 | Very often (80–99%) | In 2 conditions |
| ATP13A2ATPase cation transporting 13A2 | Very often (80–99%) | In 1 condition |
| ERLIN1ER lipid raft associated 1 | Very often (80–99%) | In 1 condition |
| FUSFUS RNA binding protein | Very often (80–99%) | In 1 condition |
| GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | Very often (80–99%) | In 1 condition |
| SIGMAR1sigma receptor chaperone 1 | Very often (80–99%) | In 1 condition |
| SORDsorbitol dehydrogenase | Very often (80–99%) | In 1 condition |
| SPG11SPG11 vesicle trafficking associated, spatacsin | Very often (80–99%) | In 1 condition |
| SPTLC1serine palmitoyltransferase long chain base subunit 1 | Very often (80–99%) | In 1 condition |
| SPTLC2serine palmitoyltransferase long chain base subunit 2 | Very often (80–99%) | In 1 condition |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Very often (80–99%) | In 1 condition |
| TARDBPTAR DNA binding protein | Very often (80–99%) | In 1 condition |
| TBCDtubulin folding cofactor D | Very often (80–99%) | In 1 condition |
| TRMT2BtRNA methyltransferase 2B | Very often (80–99%) | In 1 condition |
| UBQLN2ubiquilin 2 | Very often (80–99%) | In 1 condition |
| ACBD6acyl-CoA binding domain containing 6 | Often (30–79%) | In 1 condition |
| B4GALNT1beta-1,4-N-acetyl-galactosaminyltransferase 1 | Often (30–79%) | In 1 condition |
| CAPN1calpain 1 | Often (30–79%) | In 1 condition |
| DDHD2DDHD domain containing 2 | Often (30–79%) | In 1 condition |
| HEPACAMhepatic and glial cell adhesion molecule | Often (30–79%) | In 1 condition |
| RNF170ring finger protein 170 | Often (30–79%) | In 1 condition |
| ZFYVE26zinc finger FYVE-type containing 26 | Often (30–79%) | In 1 condition |
| CYP7B1cytochrome P450 family 7 subfamily B member 1 | Sometimes (5–29%) | In 2 conditions |
| SATB1SATB homeobox 1 | Sometimes (5–29%) | In 1 condition |
| SELENOIselenoprotein I | Sometimes (5–29%) | In 1 condition |
| THOC2THO complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| WASHC5WASH complex subunit 5 | Sometimes (5–29%) | In 2 conditions |
| CLCN4Cl-/H+ antiporter 4 | Rarely (1–4%) | In 1 condition |
| KIF5Akinesin family member 5A | Rarely (1–4%) | In 1 condition |
| RTN2reticulon 2 | Rarely (1–4%) | In 1 condition |
| UBAP1ubiquitin associated protein 1 | Rarely (1–4%) | In 1 condition |
| ACTL6Bactin like 6B | Not recorded | In 1 condition |
| ERLIN2ER lipid raft associated 2 | Not recorded | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Not recorded | In 1 condition |
| RARS2arginyl-tRNA synthetase 2, mitochondrial | Not recorded | In 1 condition |
| SPARTspartin | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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