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Gene

SELENOI

selenoprotein I

Summary

Cytogenetic location
2p23.3
Coordinates
Chromosome 2: 26,346,143–26,395,885 (GRCh38)
Exons
10 exons across 49.7 kb
Protein
397 amino acids
Also known as
KIAA1724, SELI, SEPI
Previous symbols
EPT1
MANE Select transcript
ENST00000260585.12NM_033505.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Hereditary Spastic Paraplegia

      • Hereditary Spastic Paraplegia (All Types)

        One of 66 genes linked to it

        Umbrella term covering all hereditary spastic paraplegias, including SPG4 (SPAST), the most common dominant form, and SPG5A, SPG6, SPG10, SPG18, SPG30 and SPG31.

        • 1 GenCC submitter rates it definitive or strong

    How SELENOI is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Stretches short reads find hard
    Chromosome 2, with a bracket where SELENOI sits. SELENOI and 15 genes near it on chromosome 2, from 25,871,014 to 26,871,013.Chromosome 22p23.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.326 Mb26.2 Mb26.4 Mb26.6 Mb26.8 MbASXL2: 25,733,753–25,878,600, reverse strandASXL2KIF3C: 25,926,180–25,982,761, reverse strandKIF3CRAB10: 26,033,481–26,138,575, forward strandRAB10GAREM2: 26,173,071–26,196,434, forward strandGAREM2HADHA: 26,189,833–26,245,044, reverse strandHADHAHADHB: 26,243,170–26,290,473, forward strandHADHBADGRF3: 26,308,173–26,346,817, reverse strandADGRF3SELENOI: 26,346,143–26,395,885, forward strandSELENOIDRC1: 26,401,908–26,456,717, forward strandDRC1OTOF: 26,457,203–26,558,756, reverse strandOTOFCIMIP2C: 26,562,542–26,581,178, forward strandCIMIP2CCIB4: 26,579,428–26,641,366, reverse strandCIB4KCNK3: 26,692,713–26,733,420, forward strandKCNK3SLC35F6: 26,764,240–26,781,231, forward strandSLC35F6CENPA: 26,764,289–26,801,067, forward strandCENPADPYSL5: 26,847,747–26,950,351, forward strandDPYSL5Diagram of SELENOI: 10 exons on the forward strand of chromosome 2Exon 1: 26,346,143–26,346,289, 147 basesExon 2: 26,364,302–26,364,370, 69 basesExon 3: 26,364,832–26,364,940, 109 basesExon 4: 26,367,146–26,367,220, 75 basesExon 5: 26,373,367–26,373,629, 263 basesExon 6: 26,375,040–26,375,148, 109 basesExon 7: 26,383,299–26,383,347, 49 basesExon 8: 26,384,959–26,385,139, 181 basesExon 9: 26,386,354–26,386,536, 183 basesExon 10: 26,389,005–26,395,885, 6,881 bases12468105′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 8.1 kb of the gene's 49.7 kb; 1,194 of those bases code for the protein.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). SELENOI gene: selenoprotein I. Retrieved 16 October 2026, from https://dantelabs.com/genes/selenoi

    Vancouver

    Dante Labs. SELENOI gene: selenoprotein I [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/selenoi

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