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Gene

RANBP2

RAN binding protein 2

Summary

Cytogenetic location
2q13
Coordinates
Chromosome 2: 108,719,482–108,785,809 (GRCh38)
Exons
29 exons across 66.3 kb
Protein
3,224 amino acids
Also known as
NUP358, ADANE
Previous symbols
ANE1
MANE Select transcript
ENST00000283195.11NM_006267.5
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RANBP2 yet. The test sequences your whole genome, so your data includes it all the same.

How RANBP2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where RANBP2 sits. RANBP2 and 8 genes near it on chromosome 2, from 108,252,646 to 109,252,645.Chromosome 22q13p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3108.4 Mb108.6 Mb108.8 Mb109 Mb109.2 MbSULT1C3: 108,239,968–108,266,254, forward strandSULT1C3SULT1C2: 108,288,639–108,310,568, forward strandSULT1C2SULT1C4: 108,377,911–108,388,990, forward strandSULT1C4GCC2: 108,449,107–108,509,415, forward strandGCC2LIMS1: 108,533,671–108,687,347, forward strandLIMS1RANBP2: 108,719,482–108,785,809, forward strandRANBP2CCDC138: 108,786,730–108,885,477, forward strandCCDC138EDAR: 108,894,471–108,989,372, reverse strandEDARSH3RF3: 109,128,228–109,504,638, forward strandSH3RF3Diagram of RANBP2: 29 exons on the forward strand of chromosome 2Exon 12: 1 known disease-causing siteExon 20: 1 known disease-causing siteExon 1: 108,719,482–108,719,678, 197 basesExon 2: 108,729,132–108,729,199, 68 basesExon 3: 108,730,774–108,730,885, 112 basesExon 4: 108,731,322–108,731,474, 153 basesExon 5: 108,735,532–108,735,762, 231 basesExon 6: 108,736,104–108,736,249, 146 basesExon 7: 108,740,489–108,740,681, 193 basesExon 8: 108,746,711–108,746,798, 88 basesExon 9: 108,748,920–108,749,129, 210 basesExon 10: 108,751,264–108,751,445, 182 basesExon 11: 108,751,528–108,751,703, 176 basesExon 12: 108,751,871–108,751,994, 124 basesExon 13: 108,752,998–108,753,159, 162 basesExon 14: 108,753,426–108,753,563, 138 basesExon 15: 108,753,825–108,753,971, 147 basesExon 16: 108,754,905–108,755,084, 180 basesExon 17: 108,755,176–108,755,259, 84 basesExon 18: 108,758,413–108,758,548, 136 basesExon 19: 108,762,101–108,762,195, 95 basesExon 20: 108,763,237–108,768,388, 5,152 basesExon 21: 108,771,701–108,771,871, 171 basesExon 22: 108,772,489–108,772,581, 93 basesExon 23: 108,772,868–108,773,046, 179 basesExon 24: 108,775,732–108,775,936, 205 basesExon 25: 108,777,130–108,777,231, 102 basesExon 26: 108,781,269–108,781,429, 161 basesExon 27: 108,782,128–108,782,401, 274 basesExon 28: 108,782,528–108,782,862, 335 basesExon 29: 108,783,596–108,785,809, 2,214 bases1510152025295′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 11.7 kb of the gene's 66.3 kb; 9,675 of those bases code for the protein.

How a genome test reads RANBP2

3

positions in RANBP2 where ClinVar classes a change as pathogenic or likely pathogenic

2 of them (67%) fall in regions short reads find hard.

  • Low mappability (2 sites)Regions where 100 bp or 250 bp reads cannot be placed uniquely.
  • Segmental duplications (2 sites)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.

A whole genome covers all 66.3 kb of RANBP2, introns included, not only the 11.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RANBP2 gene: RAN binding protein 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/ranbp2

Vancouver

Dante Labs. RANBP2 gene: RAN binding protein 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ranbp2

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