Trait
Confusion
Lack of clarity and coherence of thought, perception, understanding, or action.
Summary
- Also called
- Disorientation, Easily confused, Mental disorientation
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test72 genes linked to Confusion
Changes in these genes cause rare conditions in which Confusion is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| LAMB1laminin subunit beta 1 | Always | In 1 condition |
| TLR3toll like receptor 3 | Always | In 1 condition |
| UQCRHubiquinol-cytochrome c reductase hinge protein | Always | In 1 condition |
| APPamyloid beta precursor protein | Very often (80–99%) | In 1 condition |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Very often (80–99%) | In 2 conditions |
| HADHhydroxyacyl-CoA dehydrogenase | Very often (80–99%) | In 1 condition |
| PSEN1presenilin 1 | Very often (80–99%) | In 1 condition |
| PSEN2presenilin 2 | Very often (80–99%) | In 2 conditions |
| SLC22A5solute carrier family 22 member 5 | Very often (80–99%) | In 2 conditions |
| SORL1sortilin related receptor 1 | Very often (80–99%) | In 1 condition |
| TOMM40translocase of outer mitochondrial membrane 40 | Very often (80–99%) | In 1 condition |
| TRANK1tetratricopeptide repeat and ankyrin repeat containing 1 | Very often (80–99%) | In 1 condition |
| TREM2triggering receptor expressed on myeloid cells 2 | Very often (80–99%) | In 1 condition |
| APOEapolipoprotein E | Often (30–79%) | In 1 condition |
| ATP13A2ATPase cation transporting 13A2 | Often (30–79%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Often (30–79%) | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Often (30–79%) | In 2 conditions |
| CCR1C-C motif chemokine receptor 1 | Often (30–79%) | In 1 condition |
| EPM2AEPM2A glucan phosphatase, laforin | Often (30–79%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Often (30–79%) | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Often (30–79%) | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Often (30–79%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Often (30–79%) | In 1 condition |
| ERCC5ERCC excision repair 5, endonuclease | Often (30–79%) | In 1 condition |
| FASFas cell surface death receptor | Often (30–79%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Often (30–79%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Often (30–79%) | In 1 condition |
| IL10interleukin 10 | Often (30–79%) | In 1 condition |
| IL12Ainterleukin 12A | Often (30–79%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Often (30–79%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Often (30–79%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Often (30–79%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Often (30–79%) | In 1 condition |
| NAXENAD(P)HX epimerase | Often (30–79%) | In 1 condition |
| NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1 | Often (30–79%) | In 1 condition |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Often (30–79%) | In 2 conditions |
| PRRT2proline rich transmembrane protein 2 | Often (30–79%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Often (30–79%) | In 1 condition |
| SLC19A3solute carrier family 19 member 3 | Often (30–79%) | In 2 conditions |
Show 32 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SLC25A13solute carrier family 25 member 13 | Often (30–79%) | In 2 conditions |
| SLC25A15solute carrier family 25 member 15 | Often (30–79%) | In 2 conditions |
| SLC2A1solute carrier family 2 member 1 | Often (30–79%) | In 2 conditions |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 1 condition |
| TLR4toll like receptor 4 | Often (30–79%) | In 1 condition |
| TTRtransthyretin | Often (30–79%) | In 1 condition |
| UBAC2UBA domain containing 2 | Often (30–79%) | In 1 condition |
| VPS13Cvacuolar protein sorting 13 homolog C | Often (30–79%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Sometimes (5–29%) | In 1 condition |
| ALADaminolevulinate dehydratase | Sometimes (5–29%) | In 1 condition |
| ALDH4A1aldehyde dehydrogenase 4 family member A1 | Sometimes (5–29%) | In 1 condition |
| CDKN1Bcyclin dependent kinase inhibitor 1B | Sometimes (5–29%) | In 1 condition |
| CDKN2Bcyclin dependent kinase inhibitor 2B | Sometimes (5–29%) | In 1 condition |
| CTSFcathepsin F | Sometimes (5–29%) | In 1 condition |
| GNASGNAS complex locus | Sometimes (5–29%) | In 2 conditions |
| HMBShydroxymethylbilane synthase | Sometimes (5–29%) | In 1 condition |
| IVDisovaleryl-CoA dehydrogenase | Sometimes (5–29%) | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Sometimes (5–29%) | In 2 conditions |
| MEN1menin 1 | Sometimes (5–29%) | In 1 condition |
| NAGSN-acetylglutamate synthase | Sometimes (5–29%) | In 2 conditions |
| NOTCH3notch receptor 3 | Sometimes (5–29%) | In 1 condition |
| PRDM8PR/SET domain 8 | Sometimes (5–29%) | In 1 condition |
| RYR1ryanodine receptor 1 | Sometimes (5–29%) | In 1 condition |
| ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13 | Not recorded | In 1 condition |
| CHRNA2cholinergic receptor nicotinic alpha 2 subunit | Not recorded | In 1 condition |
| CPOXcoproporphyrinogen oxidase | Not recorded | In 1 condition |
| CUBNcubilin | Not recorded | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Not recorded | In 1 condition |
| MMACHCmetabolism of cobalamin associated C | Not recorded | In 1 condition |
| PRDX1peroxiredoxin 1 | Not recorded | In 1 condition |
| TBK1TANK binding kinase 1 | Not recorded | In 1 condition |
| TBPTATA-box binding protein | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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