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Gene

ALDH4A1

aldehyde dehydrogenase 4 family member A1

Summary

Cytogenetic location
1p36.13
Coordinates
Chromosome 1: 18,871,430–18,902,555 (GRCh38)
Exons
15 exons across 31.1 kb
Protein
563 amino acids
Also known as
P5CDh
Previous symbols
ALDH4
MANE Select transcript
ENST00000375341.8NM_003748.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ALDH4A1 yet. The test sequences your whole genome, so your data includes it all the same.

How ALDH4A1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where ALDH4A1 sits. ALDH4A1 and 12 genes near it on chromosome 1, from 18,386,993 to 19,386,992.Chromosome 11p36.13p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4418.4 Mb18.6 Mb18.8 Mb19 Mb19.2 MbKLHDC7A: 18,480,930–18,485,974, forward strandKLHDC7APAX7: 18,630,846–18,748,876, forward strandPAX7TAS1R2: 18,839,599–18,859,660, reverse strandTAS1R2ALDH4A1: 18,871,430–18,902,555, reverse strandALDH4A1IFFO2: 18,904,280–18,956,676, reverse strandIFFO2UBR4: 19,074,510–19,210,329, reverse strandUBR4EMC1: 19,215,660–19,251,552, reverse strandEMC1MRTO4: 19,251,555–19,260,128, forward strandMRTO4AKR7L: 19,265,982–19,274,194, reverse strandAKR7LAKR7A3: 19,281,056–19,288,823, reverse strandAKR7A3SLC66A1: 19,288,044–19,332,427, forward strandAKR7A2: 19,291,523–19,312,149, reverse strandAKR7A2CAPZB: 19,338,775–19,485,650, reverse strandCAPZBDiagram of ALDH4A1: 15 exons on the reverse strand of chromosome 1Exon 14: 1 known disease-causing siteExon 12: 2 known disease-causing sitesExon 11: 1 known disease-causing siteExon 10: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 5: 3 known disease-causing sitesExon 3: 2 known disease-causing sitesExon 2: 2 known disease-causing sitesExon 1: 2 known disease-causing sitesExon 15: 18,871,430–18,872,957, 1,528 basesExon 14: 18,874,463–18,874,581, 119 basesExon 13: 18,875,382–18,875,503, 122 basesExon 12: 18,876,315–18,876,467, 153 basesExon 11: 18,877,208–18,877,255, 48 basesExon 10: 18,877,416–18,877,612, 197 basesExon 9: 18,879,300–18,879,373, 74 basesExon 8: 18,881,700–18,881,887, 188 basesExon 7: 18,883,124–18,883,198, 75 basesExon 6: 18,883,279–18,883,428, 150 basesExon 5: 18,885,473–18,885,628, 156 basesExon 4: 18,886,464–18,886,511, 48 basesExon 3: 18,889,362–18,889,454, 93 basesExon 2: 18,890,012–18,890,105, 94 basesExon 1: 18,902,462–18,902,555, 94 bases15141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.1 kb of the gene's 31.1 kb; 1,692 of those bases code for the protein.

How a genome test reads ALDH4A1

25

positions in ALDH4A1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 31.1 kb of ALDH4A1, introns included, not only the 3.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ALDH4A1 gene: aldehyde dehydrogenase 4 family member A1. Retrieved 16 October 2026, from https://dantelabs.com/genes/aldh4a1

Vancouver

Dante Labs. ALDH4A1 gene: aldehyde dehydrogenase 4 family member A1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/aldh4a1

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