Gene
DACT1
dishevelled binding antagonist of beta catenin 1
- HGNC 17748↗(opens in a new tab)
- Ensembl gene ENSG00000165617↗(opens in a new tab)
- NCBI Gene 51339↗(opens in a new tab)
Summary
- Cytogenetic location
- 14q23.1
- Coordinates
- Chromosome 14: 58,637,962–58,648,321 (GRCh38)
- Exons
- 4 exons across 10.4 kb
- Protein
- 799 amino acids
- Also known as
- DAPPER1, THYEX3, HDPR1, DAPPER, FRODO
- MANE Select transcript
- ENST00000395153.8NM_001079520.2
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How DACT1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.8 kb of the gene's 10.4 kb; 2,400 of those bases code for the protein.
Traits linked to DACT1
The Human Phenotype Ontology lists these as features of the rare conditions DACT1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Anencephaly
- Cervical spina bifida
- Myelomeningocele
- Spinal dysraphism
- Agenesis of corpus callosum
- Chiari malformation
- Cranial nerve paralysis
- Intellectual disability
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). DACT1 gene: dishevelled binding antagonist of beta catenin 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/dact1
Dante Labs. DACT1 gene: dishevelled binding antagonist of beta catenin 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dact1
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