Traits

Traits linked to UBAP2L

ubiquitin associated protein 2 like

The Human Phenotype Ontology links 81 traits to UBAP2L, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Decreased reflex response	Always
Delayed speech and language development	Always
Drowsiness	Always
Echoing another person's speech	Always
Hyperacusis	Always
Motor delay	Always
Oromandibular dystonia	Always
Pauses in breathing while sleeping	Always
Stuttering	Always
Tremor	Always
Intellectual disability	Very often (80–99%)
Aggressive behavior	Often (30–79%)
Anxiety	Often (30–79%)
Attention deficit	Often (30–79%)
Autism spectrum disorder	Often (30–79%)
Epilepsy	Often (30–79%)
Global developmental delay	Often (30–79%)
Obsessive compulsive behavior	Often (30–79%)
Repetitive movements	Often (30–79%)
Self-injurious behavior	Often (30–79%)
Loss of developmental milestones	Sometimes (5–29%)

Abnormality of head or neck

Trait	How often it is seen
Big lower jaw	Always
Broad forehead	Always
Bulbous nose	Always
Depressed nasal tip	Always
Drooping lower lip	Always
Eye folds	Always
Flat face	Always
High palate	Always
Long face	Always
Long philtrum	Always
Low frontal hairline	Always
Medial flaring of the eyebrow	Always
Metopic synostosis	Always
Monobrow	Always
Narrow eyelid opening	Always
Round face	Always
Thin red part of the upper lip	Always
Upward slanting of the opening between the eyelids	Always
Wide nasal bridge	Always

Abnormality of limbs

Trait	How often it is seen
Broad big toe	Always
Curvature of digit	Always
Dropped arches	Always
Finger joint contracture	Always
Front half of foot turns inward	Always
Fused thumb bones	Always
Internally rotated hips	Always
Short fingers or toes	Always
Short thighbone	Always
Short toe	Always
Thenar muscle atrophy	Always

Abnormality of the eye

Trait	How often it is seen
Astigmatism	Always
Close sighted	Always
Deeply set eye	Always
Farsightedness	Always
Involuntary, rapid, rhythmic eye movements	Always
Inward turning cross eyed	Always
Outward facing eye ball	Always
Wide-set eyes	Always
Visual impairment	Sometimes (5–29%)

Abnormality of the ear

Trait	How often it is seen
Crumpled ear	Always
Cupped ear	Always
Ears rotated toward back of head	Always
Small ears	Always

Abnormality of the integument

Trait	How often it is seen
Birthmark	Always
Frontal upsweep of hair	Always
Small nail	Always
Underdeveloped toenails	Always

Abnormality of the musculoskeletal system

Trait	How often it is seen
Joint stiffness	Always
Kyphoscoliosis	Always
Low muscle tone	Often (30–79%)

Growth abnormality

Trait	How often it is seen
Prenatal growth deficiency	Always
Faltering weight	Often (30–79%)
Short stature	Often (30–79%)

Abnormality of prenatal development or birth

Trait	How often it is seen
Anhydramnios	Always
Feet or buttocks of fetus positioned near opening of uterus	Always

Abnormality of the immune system

Trait	How often it is seen
Asthma	Always
Chronic bronchitis	Always

Abnormality of the cardiovascular system

Trait	How often it is seen
Cutis marmorata	Always

Abnormality of the digestive system

Trait	How often it is seen
Feeding difficulties	Often (30–79%)

Abnormality of the genitourinary system

Trait	How often it is seen
Frequent urinary tract infections	Always

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to UBAP2L and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test