Trait

Anhydramnios

A complete or near-complete lack of amniotic fluid surrounding a fetus. This finding can be observed sonographically in the third trimesters if the deepest pocket of amniotic fluid is less than or equal to 2 cm.

HPO HP:0025700

Body system: Abnormality of prenatal development or birth

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7 genes linked to Anhydramnios

Changes in these genes cause rare conditions in which Anhydramnios is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
EXOC3L2exocyst complex component 3 like 2	Always	In 1 condition
FGF20fibroblast growth factor 20	Always	In 1 condition
GFRA1GDNF family receptor alpha 1	Always	In 1 condition
ITGA8integrin subunit alpha 8	Always	In 1 condition
UBAP2Lubiquitin associated protein 2 like	Always	In 1 condition
ROBO1roundabout guidance receptor 1	Often (30–79%)	In 1 condition
TCTN2tectonic family member 2	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of the amniotic fluid

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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