Gene
MSTO1
misato mitochondrial distribution and morphology regulator 1
- HGNC 29678↗(opens in a new tab)
- Ensembl gene ENSG00000125459↗(opens in a new tab)
- NCBI Gene 55154↗(opens in a new tab)
Summary
- Cytogenetic location
- 1q22
- Coordinates
- Chromosome 1: 155,610,218–155,614,951 (GRCh38)
- Exons
- 14 exons across 4.7 kb
- Protein
- 570 amino acids
- Also known as
- FLJ10504, LST005, MST, misato
- MANE Select transcript
- ENST00000245564.8NM_018116.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads MSTO1 yet. The test sequences your whole genome, so your data includes it all the same.
How MSTO1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.4 kb of the gene's 4.7 kb; 1,713 of those bases code for the protein.
How a genome test reads MSTO1
16
positions in MSTO1 where ClinVar classes a change as pathogenic or likely pathogenic
16 of them (100%) fall in regions short reads find hard.
- Low mappability (13 sites)Regions where 100 bp or 250 bp reads cannot be placed uniquely.
- Segmental duplications (16 sites)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.
A whole genome covers all 4.7 kb of MSTO1, introns included, not only the 2.4 kb of exons.
Traits linked to MSTO1
The Human Phenotype Ontology lists these as features of the rare conditions MSTO1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormal gait
- Anxiety
- Decreased reflex response
- Delayed speech and language development
- Depression
- Difficulty performing quick and alternating movements
- Hyperintensity of cerebral white matter on MRI
- Intellectual disability, mild
Show 13 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). MSTO1 gene: misato mitochondrial distribution and morphology regulator 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/msto1
Dante Labs. MSTO1 gene: misato mitochondrial distribution and morphology regulator 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/msto1
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