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Gene

RUSC1

RUN and SH3 domain containing 1

Summary

Cytogenetic location
1q22
Coordinates
Chromosome 1: 155,320,894–155,331,114 (GRCh38)
Exons
10 exons across 10.2 kb
Protein
902 amino acids
Also known as
NESCA
MANE Select transcript
ENST00000368352.10NM_001105203.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RUSC1 yet. The test sequences your whole genome, so your data includes it all the same.

How RUSC1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where RUSC1 sits. RUSC1 and 37 genes near it on chromosome 1, from 154,826,004 to 155,826,003.Chromosome 11q22p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44155 Mb155.2 Mb155.4 Mb155.6 Mb155.8 MbKCNN3: 154,697,455–154,870,340, reverse strandKCNN3PMVK: 154,924,732–154,937,008, reverse strandPMVKPBXIP1: 154,944,059–154,956,451, reverse strandPYGO2: 154,957,025–154,963,853, reverse strandSHC1: 154,962,284–154,974,452, reverse strandSHC1CKS1B: 154,974,641–154,979,256, forward strandCKS1BFLAD1: 154,983,311–154,993,111, forward strandFLAD1LENEP: 154,993,586–154,994,315, forward strandLENEPZBTB7B: 155,002,543–155,018,525, forward strandDCST2: 155,018,520–155,033,781, reverse strandDCST1: 155,033,824–155,050,930, forward strandADAM15: 155,050,566–155,062,780, forward strandADAM15EFNA4: 155,063,718–155,069,553, forward strandEFNA4EFNA4-EFNA3: 155,063,748–155,086,807, forward strandEFNA4-EFNA3EFNA3: 155,078,823–155,087,538, forward strandEFNA3EFNA1: 155,127,452–155,134,899, forward strandEFNA1SLC50A1: 155,135,344–155,138,857, forward strandDPM3: 155,138,457–155,140,595, reverse strandDPM3KRTCAP2: 155,169,182–155,173,475, reverse strand: 155,169,409–155,187,272, reverse strandTRIM46: 155,173,787–155,184,971, forward strandTRIM46MUC1: 155,185,824–155,192,916, reverse strandMUC1THBS3: 155,195,584–155,209,203, reverse strandTHBS3MTX1: 155,208,695–155,213,824, forward strandMTX1GBA1: 155,231,270–155,245,178, reverse strandGBA1ENTREP3: 155,247,205–155,255,824, reverse strandSCAMP3: 155,255,979–155,262,433, reverse strandSCAMP3CLK2: 155,262,747–155,278,491, reverse strandCLK2HCN3: 155,277,328–155,289,848, forward strandHCN3PKLR: 155,289,265–155,301,443, reverse strandPKLRFDPS: 155,304,786–155,320,666, forward strandFDPSRUSC1: 155,320,894–155,331,114, forward strandRUSC1ASH1L: 155,335,268–155,563,162, reverse strandASH1LMSTO1: 155,563,235–155,616,644, forward strandMSTO1: 155,626,755–155,648,640, reverse strandYY1AP1: 155,659,446–155,689,334, reverse strandYY1AP1DAP3: 155,687,833–155,740,132, forward strandDAP3GON4L: 155,749,659–155,859,439, reverse strandGON4LDiagram of RUSC1: 10 exons on the forward strand of chromosome 1Exon 1: 155,320,894–155,320,991, 98 basesExon 2: 155,321,688–155,323,130, 1,443 basesExon 3: 155,324,845–155,324,943, 99 basesExon 4: 155,325,102–155,325,178, 77 basesExon 5: 155,325,316–155,325,490, 175 basesExon 6: 155,325,567–155,325,672, 106 basesExon 7: 155,325,864–155,325,910, 47 basesExon 8: 155,326,580–155,327,132, 553 basesExon 9: 155,328,150–155,328,275, 126 basesExon 10: 155,330,403–155,331,114, 712 bases123456789105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.4 kb of the gene's 10.2 kb; 2,709 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). RUSC1 gene: RUN and SH3 domain containing 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/rusc1

Vancouver

Dante Labs. RUSC1 gene: RUN and SH3 domain containing 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rusc1

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