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Gene

YY1AP1

YY1 associated protein 1

Summary

Cytogenetic location
1q22
Coordinates
Chromosome 1: 155,659,454–155,688,774 (GRCh38)
Exons
11 exons across 29.3 kb
Protein
750 amino acids
Also known as
YY1AP, HCCA2, YAP
MANE Select transcript
ENST00000355499.9NM_139119.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads YY1AP1 yet. The test sequences your whole genome, so your data includes it all the same.

How YY1AP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where YY1AP1 sits. YY1AP1 and 30 genes near it on chromosome 1, from 155,174,114 to 156,174,113.Chromosome 11q22p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44155.2 Mb155.4 Mb155.6 Mb155.8 Mb156 Mb: 155,169,409–155,187,272, reverse strandTRIM46: 155,173,787–155,184,971, forward strandTRIM46MUC1: 155,185,824–155,192,916, reverse strandMUC1THBS3: 155,195,584–155,209,203, reverse strandTHBS3MTX1: 155,208,695–155,213,824, forward strandMTX1GBA1: 155,231,270–155,245,178, reverse strandGBA1ENTREP3: 155,247,205–155,255,824, reverse strandSCAMP3: 155,255,979–155,262,433, reverse strandSCAMP3CLK2: 155,262,747–155,278,491, reverse strandCLK2HCN3: 155,277,328–155,289,848, forward strandHCN3PKLR: 155,289,265–155,301,443, reverse strandPKLRFDPS: 155,304,786–155,320,666, forward strandFDPSRUSC1: 155,320,739–155,331,422, forward strandRUSC1ASH1L: 155,335,268–155,563,162, reverse strandASH1LMSTO1: 155,563,235–155,616,644, forward strandMSTO1: 155,626,755–155,648,640, reverse strandYY1AP1: 155,659,454–155,688,774, reverse strandYY1AP1DAP3: 155,687,833–155,740,132, forward strandDAP3GON4L: 155,749,659–155,859,439, reverse strandGON4LSYT11: 155,859,449–155,885,199, forward strandSYT11RIT1: 155,897,808–155,911,408, reverse strandRIT1KHDC4: 155,913,043–155,934,416, reverse strandKHDC4RXFP4: 155,941,638–155,943,087, forward strandRXFP4ARHGEF2: 155,944,685–156,007,070, reverse strandARHGEF2SSR2: 156,009,041–156,020,972, reverse strandSSR2UBQLN4: 156,026,961–156,053,814, reverse strandUBQLN4LAMTOR2: 156,053,916–156,058,817, forward strandLAMTOR2RAB25: 156,061,147–156,070,514, forward strandRAB25MEX3A: 156,072,013–156,082,465, reverse strandMEX3ALMNA: 156,082,572–156,140,085, forward strandLMNASEMA4A: 156,147,366–156,178,869, forward strandSEMA4ADiagram of YY1AP1: 11 exons on the reverse strand of chromosome 1Exon 9: 1 known disease-causing siteExon 5: 2 known disease-causing sitesExon 11: 155,659,454–155,660,913, 1,460 basesExon 10: 155,661,307–155,661,423, 117 basesExon 9: 155,668,627–155,668,777, 151 basesExon 8: 155,670,320–155,670,464, 145 basesExon 7: 155,672,560–155,672,731, 172 basesExon 6: 155,675,010–155,675,096, 87 basesExon 5: 155,676,548–155,676,746, 199 basesExon 4: 155,679,409–155,679,512, 104 basesExon 3: 155,680,416–155,680,456, 41 basesExon 2: 155,688,071–155,688,201, 131 basesExon 1: 155,688,659–155,688,774, 116 bases11109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 29.3 kb; 2,253 of those bases code for the protein.

How a genome test reads YY1AP1

6

positions in YY1AP1 where ClinVar classes a change as pathogenic or likely pathogenic

2 of them (33%) fall in regions short reads find hard.

  • Low mappability (1 site)Regions where 100 bp or 250 bp reads cannot be placed uniquely.
  • Segmental duplications (1 site)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.

A whole genome covers all 29.3 kb of YY1AP1, introns included, not only the 2.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). YY1AP1 gene: YY1 associated protein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/yy1ap1

Vancouver

Dante Labs. YY1AP1 gene: YY1 associated protein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/yy1ap1

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