Trait

Hand mirror movements

Clinical name: Bimanual synkinesia

Involuntary movements of one hand that accompany and mirror intentional movements of the opposite hand.

HPO HP:0001335

Also called: Mirror hand movements, Mirror movements
Body system: Abnormality of the nervous system

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33 genes linked to Hand mirror movements

Changes in these genes cause rare conditions in which Hand mirror movements is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
CEP152centrosomal protein 152	Always	In 1 condition
LARGE1LARGE xylosyl- and glucuronyltransferase 1	Always	In 1 condition
DCCDCC netrin 1 receptor	Often (30–79%)	In 4 conditions
DNAL4dynein axonemal light chain 4	Often (30–79%)	In 2 conditions
NTN1netrin 1	Often (30–79%)	In 3 conditions
RAD51RAD51 recombinase	Often (30–79%)	In 3 conditions
SVBPsmall vasohibin binding protein	Often (30–79%)	In 1 condition
ANOS1anosmin 1	Sometimes (5–29%)	In 2 conditions
CCDC141coiled-coil domain containing 141	Sometimes (5–29%)	In 1 condition
CDH2cadherin 2	Sometimes (5–29%)	In 1 condition
CHD7chromodomain helicase DNA binding protein 7	Sometimes (5–29%)	In 1 condition
DUSP6dual specificity phosphatase 6	Sometimes (5–29%)	In 1 condition
EMX2empty spiracles homeobox 2	Sometimes (5–29%)	In 1 condition
FEZF1FEZ family zinc finger 1	Sometimes (5–29%)	In 1 condition
FGF17fibroblast growth factor 17	Sometimes (5–29%)	In 1 condition
FGF8fibroblast growth factor 8	Sometimes (5–29%)	In 1 condition
FGFR1fibroblast growth factor receptor 1	Sometimes (5–29%)	In 2 conditions
FLRT3fibronectin leucine rich transmembrane protein 3	Sometimes (5–29%)	In 1 condition
GDF6growth differentiation factor 6	Sometimes (5–29%)	In 1 condition
HESX1HESX homeobox 1	Sometimes (5–29%)	In 1 condition
HS6ST1heparan sulfate 6-O-sulfotransferase 1	Sometimes (5–29%)	In 1 condition
IL17RDinterleukin 17 receptor D	Sometimes (5–29%)	In 1 condition
NDNFneuron derived neurotrophic factor	Sometimes (5–29%)	In 1 condition
PROK2prokineticin 2	Sometimes (5–29%)	In 2 conditions
PROKR2prokineticin receptor 2	Sometimes (5–29%)	In 2 conditions
ROBO1roundabout guidance receptor 1	Sometimes (5–29%)	In 1 condition
SEMA3Asemaphorin 3A	Sometimes (5–29%)	In 1 condition
SOX10SRY-box transcription factor 10	Sometimes (5–29%)	In 1 condition
SPRY4sprouty RTK signaling antagonist 4	Sometimes (5–29%)	In 1 condition
TACR3tachykinin receptor 3	Sometimes (5–29%)	In 1 condition
WDR11WD repeat domain 11	Sometimes (5–29%)	In 1 condition
TMEM147transmembrane protein 147	Rarely (1–4%)	In 1 condition
KNL1kinetochore scaffold 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Synkinesis

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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