Trait
Duane anomaly
A condition associated with a limitation of the horizontal ocular movement with retraction of the globe and narrowing of the palpebral fissure on adduction
Summary
- Also called
- Limited eye motility from Duane anomaly, Limited eye movement from Duane anomaly
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test29 genes linked to Duane anomaly
Changes in these genes cause rare conditions in which Duane anomaly is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CCNQcyclin Q | Always | In 1 condition |
| KDM2Blysine demethylase 2B | Always | In 1 condition |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Always | In 1 condition |
| POLR1ARNA polymerase I subunit A | Always | In 1 condition |
| UBA2ubiquitin like modifier activating enzyme 2 | Always | In 1 condition |
| CHN1chimerin 1 | Very often (80–99%) | In 2 conditions |
| MAFBMAF bZIP transcription factor B | Very often (80–99%) | In 2 conditions |
| SALL4spalt like transcription factor 4 | Very often (80–99%) | In 2 conditions |
| COL25A1collagen type XXV alpha 1 chain | Often (30–79%) | In 1 condition |
| DCCDCC netrin 1 receptor | Often (30–79%) | In 1 condition |
| NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor | Often (30–79%) | In 1 condition |
| ROBO3roundabout guidance receptor 3 | Often (30–79%) | In 1 condition |
| ACKR3atypical chemokine receptor 3 | Sometimes (5–29%) | In 1 condition |
| CEP120centrosomal protein 120 | Sometimes (5–29%) | In 1 condition |
| CSPP1centrosome and spindle pole associated protein 1 | Sometimes (5–29%) | In 1 condition |
| FBXO11F-box protein 11 | Sometimes (5–29%) | In 1 condition |
| KCNN2potassium calcium-activated channel subfamily N member 2 | Sometimes (5–29%) | In 1 condition |
| KIAA0586KIAA0586 | Sometimes (5–29%) | In 1 condition |
| MED13mediator complex subunit 13 | Sometimes (5–29%) | In 1 condition |
| SALL1spalt like transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| DNM1Ldynamin 1L | Rarely (1–4%) | In 1 condition |
| GJA5gap junction protein alpha 5 | Rarely (1–4%) | In 1 condition |
| GJA8gap junction protein alpha 8 | Rarely (1–4%) | In 1 condition |
| OPA1OPA1 mitochondrial dynamin like GTPase | Rarely (1–4%) | In 1 condition |
| PPIBpeptidylprolyl isomerase B | Rarely (1–4%) | In 1 condition |
| ARXaristaless related homeobox | Not recorded | In 1 condition |
| HOXA1homeobox A1 | Not recorded | In 1 condition |
| MN1MN1 proto-oncogene, transcriptional regulator | Not recorded | In 1 condition |
| ZMIZ1zinc finger MIZ-type containing 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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