Trait
Prolonged bleeding time
Prolongation of the time taken for a standardized skin cut of fixed depth and length to stop bleeding.
Summary
- Also called
- Increased bleeding time
Reference genomeGRCh38hg38
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Get my Genome Test48 genes linked to Prolonged bleeding time
Changes in these genes cause rare conditions in which Prolonged bleeding time is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AP3B1adaptor related protein complex 3 subunit beta 1 | Always | In 1 condition |
| CREB3L1cAMP responsive element binding protein 3 like 1 | Always | In 1 condition |
| DTNBP1dystrobrevin binding protein 1 | Always | In 1 condition |
| GFI1Bgrowth factor independent 1B transcriptional repressor | Always | In 1 condition |
| GP6glycoprotein VI platelet | Always | In 1 condition |
| HPS5HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 | Always | In 1 condition |
| HPS6HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 | Always | In 1 condition |
| RASGRP2RAS guanyl releasing protein 2 | Always | In 1 condition |
| RIN2Ras and Rab interactor 2 | Always | In 1 condition |
| RUNX1RUNX family transcription factor 1 | Always | In 1 condition |
| THBS2thrombospondin 2 | Always | In 1 condition |
| CALRcalreticulin | Very often (80–99%) | In 1 condition |
| GATA2GATA binding protein 2 | Very often (80–99%) | In 1 condition |
| ITGA2Bintegrin subunit alpha 2b | Very often (80–99%) | In 2 conditions |
| ITGB3integrin subunit beta 3 | Very often (80–99%) | In 2 conditions |
| JAK2Janus kinase 2 | Very often (80–99%) | In 1 condition |
| MPLMPL proto-oncogene, thrombopoietin receptor | Very often (80–99%) | In 1 condition |
| SH2B3SH2B adaptor protein 3 | Very often (80–99%) | In 1 condition |
| SLC35A1solute carrier family 35 member A1 | Very often (80–99%) | In 1 condition |
| TEKTEK receptor tyrosine kinase | Very often (80–99%) | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Very often (80–99%) | In 1 condition |
| TP53tumor protein p53 | Very often (80–99%) | In 1 condition |
| WASWASP actin nucleation promoting factor | Very often (80–99%) | In 2 conditions |
| FYB1FYN binding protein 1 | Often (30–79%) | In 1 condition |
| MAP2K2mitogen-activated protein kinase kinase 2 | Often (30–79%) | In 1 condition |
| MYH9myosin heavy chain 9 | Often (30–79%) | In 2 conditions |
| MYRFmyelin regulatory factor | Often (30–79%) | In 1 condition |
| NF1neurofibromin 1 | Often (30–79%) | In 1 condition |
| AGGF1angiogenic factor with G-patch and FHA domains 1 | Sometimes (5–29%) | In 1 condition |
| BMS1BMS1 ribosome biogenesis factor | Sometimes (5–29%) | In 1 condition |
| COL1A1collagen type I alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| COL5A1collagen type V alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| COL5A2collagen type V alpha 2 chain | Sometimes (5–29%) | In 1 condition |
| DLL4delta like canonical Notch ligand 4 | Sometimes (5–29%) | In 1 condition |
| ITGB4integrin subunit beta 4 | Sometimes (5–29%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| PLECplectin | Sometimes (5–29%) | In 1 condition |
| UBA2ubiquitin like modifier activating enzyme 2 | Sometimes (5–29%) | In 1 condition |
| CD36CD36 molecule (CD36 blood group) | Not recorded | In 1 condition |
| F2coagulation factor II, thrombin | Not recorded | In 1 condition |
Show 8 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| F5coagulation factor V | Not recorded | In 1 condition |
| GATA1GATA binding protein 1 | Not recorded | In 1 condition |
| GP1BAglycoprotein Ib platelet subunit alpha | Not recorded | In 2 conditions |
| GP1BBglycoprotein Ib platelet subunit beta | Not recorded | In 1 condition |
| GP9glycoprotein IX platelet | Not recorded | In 1 condition |
| HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 | Not recorded | In 1 condition |
| NBEAL2neurobeachin like 2 | Not recorded | In 1 condition |
| VWFvon Willebrand factor | Not recorded | In 2 conditions |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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