Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

THBS2

thrombospondin 2

Summary

Cytogenetic location
6q27
Coordinates
Chromosome 6: 169,215,785–169,253,846 (GRCh38)
Exons
22 exons across 38.1 kb
Protein
1,172 amino acids
Also known as
TSP2
MANE Select transcript
ENST00000617924.6NM_003247.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads THBS2 yet. The test sequences your whole genome, so your data includes it all the same.

How THBS2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 6, with a bracket where THBS2 sits. THBS2 and 4 genes near it on chromosome 6, from 168,734,816 to 169,734,815.Chromosome 66q27p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q27168.8 Mb169 Mb169.2 Mb169.4 Mb169.6 MbTHBS2: 169,215,785–169,253,846, reverse strandTHBS2: 169,419,969–169,702,047, reverse strandWDR27: 169,457,211–169,702,729, reverse strandWDR27C6orf120: 169,702,126–169,706,360, forward strandC6orf120PHF10: 169,703,902–169,725,566, reverse strandPHF10Diagram of THBS2: 22 exons on the reverse strand of chromosome 6Exon 17: 1 known disease-causing siteExon 22: 169,215,785–169,217,829, 2,045 basesExon 21: 169,220,198–169,220,337, 140 basesExon 20: 169,221,430–169,221,527, 98 basesExon 19: 169,222,197–169,222,468, 272 basesExon 18: 169,223,248–169,223,475, 228 basesExon 17: 169,225,145–169,225,379, 235 basesExon 16: 169,226,180–169,226,298, 119 basesExon 15: 169,228,122–169,228,281, 160 basesExon 14: 169,229,572–169,229,679, 108 basesExon 13: 169,231,980–169,232,198, 219 basesExon 12: 169,232,664–169,232,816, 153 basesExon 11: 169,232,890–169,233,017, 128 basesExon 10: 169,234,734–169,234,907, 174 basesExon 9: 169,237,170–169,237,346, 177 basesExon 8: 169,237,625–169,237,795, 171 basesExon 7: 169,239,599–169,239,695, 97 basesExon 6: 169,240,452–169,240,592, 141 basesExon 5: 169,241,762–169,241,958, 197 basesExon 4: 169,246,197–169,246,281, 85 basesExon 3: 169,248,417–169,248,973, 557 basesExon 2: 169,250,733–169,250,806, 74 basesExon 1: 169,253,724–169,253,846, 123 bases22201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.7 kb of the gene's 38.1 kb; 3,519 of those bases code for the protein.

How a genome test reads THBS2

1

position in THBS2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 38.1 kb of THBS2, introns included, not only the 5.7 kb of exons.

Traits linked to THBS2

The Human Phenotype Ontology lists these as features of the rare conditions THBS2 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). THBS2 gene: thrombospondin 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/thbs2

Vancouver

Dante Labs. THBS2 gene: thrombospondin 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/thbs2

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test