Gene
IGKC
immunoglobulin kappa constant
- HGNC 5716(opens in a new tab)
- Ensembl gene ENSG00000211592(opens in a new tab)
- NCBI Gene 3514(opens in a new tab)
Summary
- Cytogenetic location
- 2p11.2
- Also known as
- HCAK1
- Locus type
- immunoglobulin gene
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Traits linked to IGKC
The Human Phenotype Ontology lists these as features of the rare conditions IGKC can cause. Each trait's page lists the other genes linked to it.
Abnormality of the immune system
- Recurrent infections
- Recurrent respiratory infections
- Asthma
- Autoimmunity
- Recurrent bacterial infections
- Recurrent chest infections
- Severe infection
- Baby eczema
Show 13 more traits
- Bronchitis
- Pneumonia
- Recurrent pneumonia
- Recurrent streptococcal infections
- Systemic lupus erythematosus
- Decreased circulating specific pneumococcal antibody concentration
- Food allergy
- Infection in blood stream
- Psoriasiform dermatitis
- Pulmonary tuberculosis
- Recurrent shingles
- Skin rash
- Susceptibility to herpesvirus
External links
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). IGKC gene: immunoglobulin kappa constant. Retrieved 17 October 2026, from https://dantelabs.com/genes/igkc
Dante Labs. IGKC gene: immunoglobulin kappa constant [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/igkc
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