Trait
Long nose
Distance from nasion to subnasale more than two standard deviations above the mean, or alternatively, an apparently increased length from the nasal root to the nasal base.
Summary
- Also called
- Elongated nose, Increased height of nose, Increased length of nose, Increased nasal height, Increased nasal length, Nasal elongation
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test46 genes linked to Long nose
Changes in these genes cause rare conditions in which Long nose is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GINS3GINS complex subunit 3 | Always | In 1 condition |
| INPP4Ainositol polyphosphate-4-phosphatase type I A | Always | In 1 condition |
| JAG1jagged canonical Notch ligand 1 | Always | In 1 condition |
| NEXMIFneurite extension and migration factor | Always | In 1 condition |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| THOC6THO complex subunit 6 | Always | In 2 conditions |
| ZBTB18zinc finger and BTB domain containing 18 | Always | In 1 condition |
| AP1S2adaptor related protein complex 1 subunit sigma 2 | Very often (80–99%) | In 1 condition |
| KAT6Blysine acetyltransferase 6B | Very often (80–99%) | In 1 condition |
| RNU4ATACRNA, U4atac small nuclear | Very often (80–99%) | In 1 condition |
| SCUBE3signal peptide, CUB domain and EGF like domain containing 3 | Very often (80–99%) | In 1 condition |
| ACTBactin beta | Often (30–79%) | In 1 condition |
| ACTG1actin gamma 1 | Often (30–79%) | In 1 condition |
| FRA10AC1FRA10A associated CGG repeat 1 | Often (30–79%) | In 1 condition |
| NDC1NDC1 transmembrane nucleoporin | Often (30–79%) | In 1 condition |
| NOGnoggin | Often (30–79%) | In 1 condition |
| SMG9SMG9 nonsense mediated mRNA decay factor | Often (30–79%) | In 1 condition |
| SOX11SRY-box transcription factor 11 | Often (30–79%) | In 1 condition |
| AFG2AAAA ATPase AFG2A | Sometimes (5–29%) | In 1 condition |
| ASXL3ASXL transcriptional regulator 3 | Sometimes (5–29%) | In 1 condition |
| EXTL3exostosin like glycosyltransferase 3 | Sometimes (5–29%) | In 1 condition |
| GABRA3gamma-aminobutyric acid type A receptor subunit alpha3 | Sometimes (5–29%) | In 1 condition |
| PAN2poly(A) specific ribonuclease subunit PAN2 | Sometimes (5–29%) | In 1 condition |
| PIGSphosphatidylinositol glycan anchor biosynthesis class S | Sometimes (5–29%) | In 1 condition |
| PIGUphosphatidylinositol glycan anchor biosynthesis class U | Sometimes (5–29%) | In 1 condition |
| POLEDNA polymerase epsilon, catalytic subunit | Sometimes (5–29%) | In 1 condition |
| RECQL4RecQ like helicase 4 | Sometimes (5–29%) | In 1 condition |
| SRCAPSnf2 related CREBBP activator protein | Sometimes (5–29%) | In 1 condition |
| TRPM3transient receptor potential cation channel subfamily M member 3 | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| ZMYM2zinc finger MYM-type containing 2 | Sometimes (5–29%) | In 1 condition |
| ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase | Not recorded | In 1 condition |
| AP4E1adaptor related protein complex 4 subunit epsilon 1 | Not recorded | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Not recorded | In 1 condition |
| GJA1gap junction protein alpha 1 | Not recorded | In 1 condition |
| MED12mediator complex subunit 12 | Not recorded | In 1 condition |
| NBNnibrin | Not recorded | In 1 condition |
| NOTCH2notch receptor 2 | Not recorded | In 1 condition |
| OPHN1oligophrenin 1 | Not recorded | In 1 condition |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Not recorded | In 1 condition |
Show 6 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SATB2SATB homeobox 2 | Not recorded | In 1 condition |
| SETD2SET domain containing 2, histone lysine methyltransferase | Not recorded | In 1 condition |
| SLC9A6solute carrier family 9 member A6 | Not recorded | In 1 condition |
| SOX18SRY-box transcription factor 18 | Not recorded | In 1 condition |
| TWIST1twist family bHLH transcription factor 1 | Not recorded | In 2 conditions |
| XRCC4X-ray repair cross complementing 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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