Gene
KAT6B
lysine acetyltransferase 6B
- HGNC 17582(opens in a new tab)
- Ensembl gene ENSG00000156650(opens in a new tab)
- NCBI Gene 23522(opens in a new tab)
Summary
- Cytogenetic location
- 10q22.2
- Coordinates
- Chromosome 10: 74,826,600–75,032,624 (GRCh38)
- Exons
- 18 exons across 206 kb
- Protein
- 2,073 amino acids
- Also known as
- querkopf, qkf, Morf, MOZ2
- Previous symbols
- MYST4
- MANE Select transcript
- ENST00000287239.10NM_012330.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads KAT6B yet. The test sequences your whole genome, so your data includes it all the same.
How KAT6B is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 8.3 kb of the gene's 206 kb; 6,222 of those bases code for the protein.
How a genome test reads KAT6B
98
positions in KAT6B where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 206 kb of KAT6B, introns included, not only the 8.3 kb of exons.
Traits linked to KAT6B
The Human Phenotype Ontology lists these as features of the rare conditions KAT6B can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Abnormally small head
- Bulbous nose
- Coarse facial features
- Little lower jaw
- Long nose
- Narrow opening between the eyelids
- Prominent back of the head
- Prominent nasal bridge
Show 20 more traits
- Prominent nose
- Receding chin
- Short opening between the eyelids
- Sloping forehead
- Wide nose
- Abnormality of the cheek
- Bifid uvula
- Cleft palate
- Delayed eruption of teeth
- Long philtrum
- Sparse scalp hair
- Submucous cleft hard palate
- Wide nasal bridge
- Abnormal nasolacrimal system morphology
- Neoplasm of the tongue
- Decreased size of tooth
- Depressed nasal bridge
- Downward slanting of the opening between the eyelids
- Epicanthus inversus
- Thin red part of the upper lip
Abnormality of the genitourinary system
- Smaller than typical growth of scrotum
- Underdeveloped labia
- Undescended testes
- Enlarged clitoris
- Hydronephrosis
- Multicystic kidney dysplasia
- Hypospadias
- Enlarged labia minora
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). KAT6B gene: lysine acetyltransferase 6B. Retrieved 16 October 2026, from https://dantelabs.com/genes/kat6b
Dante Labs. KAT6B gene: lysine acetyltransferase 6B [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/kat6b
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