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Gene

PIGU

phosphatidylinositol glycan anchor biosynthesis class U

Summary

Cytogenetic location
20q11.22
Coordinates
Chromosome 20: 34,560,542–34,677,092 (GRCh38)
Exons
12 exons across 116.6 kb
Protein
435 amino acids
Also known as
bA346K17.2, GAB1, PIG-U
Previous symbols
CDC91L1
MANE Select transcript
ENST00000217446.8NM_080476.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PIGU yet. The test sequences your whole genome, so your data includes it all the same.

How PIGU is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 20, with a bracket where PIGU sits. PIGU and 14 genes near it on chromosome 20, from 34,118,817 to 35,118,816.Chromosome 2020q11.22p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.3334.2 Mb34.4 Mb34.6 Mb34.8 Mb35 MbASIP: 34,194,569–34,269,346, forward strandASIPAHCY: 34,280,263–34,311,802, reverse strandAHCYITCH: 34,363,235–34,511,773, forward strandITCH: 34,363,271–34,540,923, forward strandDYNLRB1: 34,515,600–34,540,958, forward strandDYNLRB1MAP1LC3A: 34,546,838–34,560,357, forward strandMAP1LC3APIGU: 34,560,542–34,677,092, reverse strandPIGUNCOA6: 34,689,097–34,825,739, reverse strandNCOA6TP53INP2: 34,701,662–34,713,442, forward strandTP53INP2GGT7: 34,844,714–34,872,888, reverse strandGGT7ACSS2: 34,872,146–34,927,962, forward strandACSS2GSS: 34,928,432–34,956,027, reverse strandGSSMYH7B: 34,955,810–35,002,440, forward strandMYH7BTRPC4AP: 34,995,209–35,092,868, reverse strandTRPC4APEDEM2: 35,113,122–35,147,404, reverse strandEDEM2Diagram of PIGU: 12 exons on the reverse strand of chromosome 20Exon 12: 1 known disease-causing siteExon 12: 34,560,542–34,560,979, 438 basesExon 11: 34,575,104–34,575,246, 143 basesExon 10: 34,581,548–34,581,672, 125 basesExon 9: 34,585,437–34,585,580, 144 basesExon 8: 34,588,453–34,588,607, 155 basesExon 7: 34,616,042–34,616,139, 98 basesExon 6: 34,634,615–34,634,715, 101 basesExon 5: 34,637,876–34,637,985, 110 basesExon 4: 34,644,164–34,644,226, 63 basesExon 3: 34,645,275–34,645,334, 60 basesExon 2: 34,657,180–34,657,244, 65 basesExon 1: 34,676,956–34,677,092, 137 bases1210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 116.6 kb; 1,308 of those bases code for the protein.

How a genome test reads PIGU

1

position in PIGU where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 116.6 kb of PIGU, introns included, not only the 1.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PIGU gene: phosphatidylinositol glycan anchor biosynthesis class U. Retrieved 17 October 2026, from https://dantelabs.com/genes/pigu

Vancouver

Dante Labs. PIGU gene: phosphatidylinositol glycan anchor biosynthesis class U [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pigu

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