Trait
Broad palm
For children from birth to 4 years of age the palm width is more than 2 SD above the mean; for children from 4 to 16 years of age the palm width is above the 95th centile; or, the width of the palm appears disproportionately wide for the length.
Summary
- Also called
- Broad hand, Broad hands, Wide palm
- Body system
- Abnormality of limbs
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test35 genes linked to Broad palm
Changes in these genes cause rare conditions in which Broad palm is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| B3GLCTbeta 3-glucosyltransferase | Always | In 1 condition |
| DDR2discoidin domain receptor tyrosine kinase 2 | Always | In 1 condition |
| DYNC1H1dynein cytoplasmic 1 heavy chain 1 | Always | In 1 condition |
| FGD1FYVE, RhoGEF and PH domain containing 1 | Always | In 2 conditions |
| TOMM7translocase of outer mitochondrial membrane 7 | Always | In 1 condition |
| BCORBCL6 corepressor | Often (30–79%) | In 1 condition |
| DLG5discs large MAGUK scaffold protein 5 | Often (30–79%) | In 1 condition |
| GNSglucosamine (N-acetyl)-6-sulfatase | Often (30–79%) | In 1 condition |
| KDM6Blysine demethylase 6B | Often (30–79%) | In 1 condition |
| LBRlamin B receptor | Often (30–79%) | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Often (30–79%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Often (30–79%) | In 1 condition |
| PTH1Rparathyroid hormone 1 receptor | Often (30–79%) | In 1 condition |
| RAI1retinoic acid induced 1 | Often (30–79%) | In 2 conditions |
| DHX30DExH-box helicase 30 | Sometimes (5–29%) | In 1 condition |
| SLC35C1solute carrier family 35 member C1 | Sometimes (5–29%) | In 1 condition |
| SRRM2serine/arginine repetitive matrix 2 | Sometimes (5–29%) | In 1 condition |
| TONSLtonsoku like, DNA repair protein | Sometimes (5–29%) | In 1 condition |
| CTCFCCCTC-binding factor | Rarely (1–4%) | In 1 condition |
| ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10 | Not recorded | In 1 condition |
| AIFM1apoptosis inducing factor mitochondria associated 1 | Not recorded | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Not recorded | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Not recorded | In 1 condition |
| DYMdymeclin | Not recorded | In 1 condition |
| FBN1fibrillin 1 | Not recorded | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Not recorded | In 1 condition |
| FHL1four and a half LIM domains 1 | Not recorded | In 1 condition |
| GPC3glypican 3 | Not recorded | In 1 condition |
| IFT80intraflagellar transport 80 | Not recorded | In 1 condition |
| IHHIndian hedgehog signaling molecule | Not recorded | In 1 condition |
| PPP2R3Cprotein phosphatase 2 regulatory subunit B''gamma | Not recorded | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Not recorded | In 1 condition |
| RPS6KA3ribosomal protein S6 kinase A3 | Not recorded | In 1 condition |
| SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1 like | Not recorded | In 1 condition |
| TBL1XR1TBL1X/Y related 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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