Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

SIAE

sialic acid acetylesterase

Summary

Cytogenetic location
11q24.2
Coordinates
Chromosome 11: 124,633,113–124,673,739 (GRCh38)
Exons
10 exons across 40.6 kb
Protein
523 amino acids
Also known as
CSE-C, MGC87009, LSE
Previous symbols
YSG2
MANE Select transcript
ENST00000263593.8NM_170601.5
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads SIAE yet. The test sequences your whole genome, so your data includes it all the same.

How SIAE is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where SIAE sits. SIAE and 27 genes near it on chromosome 11, from 124,153,426 to 125,153,425.Chromosome 1111q24.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25124.2 Mb124.4 Mb124.6 Mb124.8 Mb125 MbOR10D3: 124,183,345–124,188,780, forward strandOR10D3OR8G3: 124,211,707–124,215,828, forward strandOR8G3OR8G2P: 124,224,732–124,225,666, forward strandOR8G2POR8G1: 124,241,095–124,254,364, forward strandOR8G1OR8G5: 124,256,376–124,266,224, forward strandOR8G5OR8D1: 124,302,831–124,315,099, reverse strandOR8D1OR8D2: 124,319,262–124,320,197, reverse strandOR8D2OR8B2: 124,382,394–124,384,499, reverse strandOR8B2OR8B3: 124,395,534–124,399,024, reverse strandOR8B3OR8B4: 124,423,942–124,424,871, reverse strandOR8B4OR8B8: 124,437,445–124,445,696, reverse strandOR8B8OR8B12: 124,539,635–124,545,333, reverse strandOR8B12OR8A1: 124,566,660–124,582,942, forward strandOR8A1PANX3: 124,611,428–124,620,356, forward strandPANX3FYRD1: 124,622,792–124,648,640, forward strandFYRD1SIAE: 124,633,113–124,673,739, reverse strandSIAESPA17: 124,673,327–124,698,312, forward strandSPA17NRGN: 124,739,939–124,749,342, forward strandNRGNVSIG2: 124,747,472–124,752,274, reverse strandVSIG2ESAM: 124,752,583–124,762,323, reverse strandESAMMSANTD2: 124,764,684–124,800,706, reverse strandMSANTD2ROBO3: 124,865,413–124,881,471, forward strandROBO3ROBO4: 124,883,666–124,898,500, reverse strandROBO4HEPACAM: 124,919,205–124,936,431, reverse strandHEPACAMHEPN1: 124,919,250–124,920,677, forward strandHEPN1CCDC15: 124,954,056–125,041,649, forward strandCCDC15SLC37A2: 125,063,067–125,090,516, forward strandSLC37A2TMEM218: 125,094,379–125,111,870, reverse strandTMEM218Diagram of SIAE: 10 exons on the reverse strand of chromosome 11Exon 10: 124,633,113–124,637,202, 4,090 basesExon 9: 124,638,542–124,638,737, 196 basesExon 8: 124,639,710–124,639,867, 158 basesExon 7: 124,647,365–124,647,498, 134 basesExon 6: 124,648,066–124,648,175, 110 basesExon 5: 124,649,619–124,649,796, 178 basesExon 4: 124,654,655–124,654,793, 139 basesExon 3: 124,660,628–124,660,803, 176 basesExon 2: 124,669,360–124,669,521, 162 basesExon 1: 124,673,642–124,673,739, 98 bases109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.4 kb of the gene's 40.6 kb; 1,572 of those bases code for the protein.

Sequencing SIAE

1Low

How hard SIAE is to sequence with short reads, out of 100

  • Mappability0.1%
  • Homology0%
  • Repeats2.3%
  • GC content7.5%
  • Reference coverage0%

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). SIAE gene: sialic acid acetylesterase. Retrieved 17 October 2026, from https://dantelabs.com/genes/siae

Vancouver

Dante Labs. SIAE gene: sialic acid acetylesterase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/siae

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test