Trait
Obstructive lung disease
Clinical name: Airway obstruction
Obstruction of conducting airways of the lung.
Summary
- Also called
- Pulmonary obstruction
- Body system
- Abnormality of the respiratory system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Obstructive lung disease, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test96 genes linked to Obstructive lung disease
Changes in these genes cause rare conditions in which Obstructive lung disease is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CEACAM3CEA cell adhesion molecule 3 | Very often (80–99%) | In 1 condition |
| CEACAM6CEA cell adhesion molecule 6 | Very often (80–99%) | In 1 condition |
| CFTRCF transmembrane conductance regulator | Very often (80–99%) | In 1 condition |
| CLCA4chloride channel accessory 4 | Very often (80–99%) | In 1 condition |
| DCTN4dynactin subunit 4 | Very often (80–99%) | In 1 condition |
| EDNRAendothelin receptor type A | Very often (80–99%) | In 1 condition |
| GCLCglutamate-cysteine ligase catalytic subunit | Very often (80–99%) | In 1 condition |
| GSTM3glutathione S-transferase mu 3 | Very often (80–99%) | In 1 condition |
| HFEhomeostatic iron regulator | Very often (80–99%) | In 1 condition |
| HMOX1heme oxygenase 1 | Very often (80–99%) | In 1 condition |
| KCNN4potassium calcium-activated channel subfamily N member 4 | Very often (80–99%) | In 1 condition |
| MIFmacrophage migration inhibitory factor | Very often (80–99%) | In 1 condition |
| NFIXnuclear factor I X | Very often (80–99%) | In 1 condition |
| SERPINA1serpin family A member 1 | Very often (80–99%) | In 1 condition |
| SLC11A1solute carrier family 11 member 1 | Very often (80–99%) | In 1 condition |
| SLC26A9solute carrier family 26 member 9 | Very often (80–99%) | In 1 condition |
| SLC6A14solute carrier family 6 member 14 | Very often (80–99%) | In 1 condition |
| SLC9A3solute carrier family 9 member A3 | Very often (80–99%) | In 1 condition |
| STX1Asyntaxin 1A | Very often (80–99%) | In 1 condition |
| TGFB1transforming growth factor beta 1 | Very often (80–99%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Often (30–79%) | In 1 condition |
| EIF4A3eukaryotic translation initiation factor 4A3 | Often (30–79%) | In 1 condition |
| FBN1fibrillin 1 | Often (30–79%) | In 1 condition |
| GUSBglucuronidase beta | Often (30–79%) | In 1 condition |
| LTBP3latent transforming growth factor beta binding protein 3 | Often (30–79%) | In 1 condition |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Often (30–79%) | In 1 condition |
| APCAPC regulator of Wnt signaling pathway | Sometimes (5–29%) | In 1 condition |
| BRWD1bromodomain and WD repeat domain containing 1 | Sometimes (5–29%) | In 1 condition |
| CCDC39coiled-coil domain 39 molecular ruler complex subunit | Sometimes (5–29%) | In 1 condition |
| CCDC40coiled-coil domain 40 molecular ruler complex subunit | Sometimes (5–29%) | In 1 condition |
| CCNOcyclin O | Sometimes (5–29%) | In 1 condition |
| CFAP221cilia and flagella associated protein 221 | Sometimes (5–29%) | In 1 condition |
| CFAP298cilia and flagella associated protein 298 | Sometimes (5–29%) | In 1 condition |
| CFAP300cilia and flagella associated protein 300 | Sometimes (5–29%) | In 1 condition |
| CFAP74cilia and flagella associated protein 74 | Sometimes (5–29%) | In 1 condition |
| CLXNcalaxin | Sometimes (5–29%) | In 1 condition |
| DAW1dynein assembly factor with WD repeats 1 | Sometimes (5–29%) | In 1 condition |
| DNAAF1dynein axonemal assembly factor 1 | Sometimes (5–29%) | In 1 condition |
| DNAAF11dynein axonemal assembly factor 11 | Sometimes (5–29%) | In 1 condition |
| DNAAF19dynein axonemal assembly factor 19 | Sometimes (5–29%) | In 1 condition |
Show 56 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| DNAAF2dynein axonemal assembly factor 2 | Sometimes (5–29%) | In 1 condition |
| DNAAF3dynein axonemal assembly factor 3 | Sometimes (5–29%) | In 1 condition |
| DNAAF4dynein axonemal assembly factor 4 | Sometimes (5–29%) | In 1 condition |
| DNAAF5dynein axonemal assembly factor 5 | Sometimes (5–29%) | In 1 condition |
| DNAAF6dynein axonemal assembly factor 6 | Sometimes (5–29%) | In 1 condition |
| DNAH1dynein axonemal heavy chain 1 | Sometimes (5–29%) | In 1 condition |
| DNAH11dynein axonemal heavy chain 11 | Sometimes (5–29%) | In 1 condition |
| DNAH5dynein axonemal heavy chain 5 | Sometimes (5–29%) | In 1 condition |
| DNAH7dynein axonemal heavy chain 7 | Sometimes (5–29%) | In 1 condition |
| DNAH9dynein axonemal heavy chain 9 | Sometimes (5–29%) | In 1 condition |
| DNAI1dynein axonemal intermediate chain 1 | Sometimes (5–29%) | In 1 condition |
| DNAI2dynein axonemal intermediate chain 2 | Sometimes (5–29%) | In 1 condition |
| DNAJB13DnaJ heat shock protein family (Hsp40) member B13 | Sometimes (5–29%) | In 1 condition |
| DNAL1dynein axonemal light chain 1 | Sometimes (5–29%) | In 1 condition |
| DNASE1L3deoxyribonuclease 1L3 | Sometimes (5–29%) | In 1 condition |
| DRC1dynein regulatory complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| DRC2dynein regulatory complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| DRC4dynein regulatory complex subunit 4 | Sometimes (5–29%) | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Sometimes (5–29%) | In 1 condition |
| FOXJ1forkhead box J1 | Sometimes (5–29%) | In 1 condition |
| GAS2L2growth arrest specific 2 like 2 | Sometimes (5–29%) | In 1 condition |
| HYDINHYDIN axonemal central pair apparatus protein | Sometimes (5–29%) | In 1 condition |
| IDSiduronate 2-sulfatase | Sometimes (5–29%) | In 1 condition |
| KIF22kinesin family member 22 | Sometimes (5–29%) | In 1 condition |
| LRRC56leucine rich repeat containing 56 | Sometimes (5–29%) | In 1 condition |
| MCIDASmulticiliate differentiation and DNA synthesis associated cell cycle protein | Sometimes (5–29%) | In 1 condition |
| NEK10NIMA related kinase 10 | Sometimes (5–29%) | In 1 condition |
| NME5NME/NM23 family member 5 | Sometimes (5–29%) | In 1 condition |
| NME8NME/NM23 family member 8 | Sometimes (5–29%) | In 1 condition |
| ODAD1outer dynein arm docking complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| ODAD2outer dynein arm docking complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| ODAD3outer dynein arm docking complex subunit 3 | Sometimes (5–29%) | In 1 condition |
| ODAD4outer dynein arm docking complex subunit 4 | Sometimes (5–29%) | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Sometimes (5–29%) | In 1 condition |
| POGLUT1protein O-glucosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| RPGRretinitis pigmentosa GTPase regulator | Sometimes (5–29%) | In 1 condition |
| RSPH1radial spoke head component 1 | Sometimes (5–29%) | In 1 condition |
| RSPH3radial spoke head 3 | Sometimes (5–29%) | In 1 condition |
| RSPH4Aradial spoke head component 4A | Sometimes (5–29%) | In 1 condition |
| RSPH9radial spoke head component 9 | Sometimes (5–29%) | In 1 condition |
| SLC26A2solute carrier family 26 member 2 | Sometimes (5–29%) | In 1 condition |
| SPAG1sperm associated antigen 1 | Sometimes (5–29%) | In 1 condition |
| SPEF2sperm flagellar and cilia associated 2 | Sometimes (5–29%) | In 1 condition |
| STK36serine/threonine kinase 36 | Sometimes (5–29%) | In 1 condition |
| TLL1tolloid like 1 | Sometimes (5–29%) | In 2 conditions |
| TTC12tetratricopeptide repeat domain 12 | Sometimes (5–29%) | In 1 condition |
| ZMYND10zinc finger MYND-type containing 10 | Sometimes (5–29%) | In 1 condition |
| ACTC1actin alpha cardiac muscle 1 | Rarely (1–4%) | In 1 condition |
| CITED2Cbp/p300 interacting transactivator with ED-rich tail 2 | Rarely (1–4%) | In 2 conditions |
| GATA4GATA binding protein 4 | Rarely (1–4%) | In 1 condition |
| GATA6GATA binding protein 6 | Rarely (1–4%) | In 1 condition |
| MYH6myosin heavy chain 6 | Rarely (1–4%) | In 1 condition |
| NKX2-5NK2 homeobox 5 | Rarely (1–4%) | In 1 condition |
| TBX20T-box transcription factor 20 | Rarely (1–4%) | In 1 condition |
| GLAgalactosidase alpha | Not recorded | In 1 condition |
| MGPmatrix Gla protein | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks