Gene
KIF22
kinesin family member 22
- HGNC 6391↗(opens in a new tab)
- Ensembl gene ENSG00000079616↗(opens in a new tab)
- NCBI Gene 3835↗(opens in a new tab)
Summary
- Cytogenetic location
- 16p11.2
- Coordinates
- Chromosome 16: 29,790,751–29,805,384 (GRCh38)
- Exons
- 14 exons across 14.6 kb
- Protein
- 665 amino acids
- Also known as
- Kid, OBP-1, OBP-2
- Previous symbols
- KNSL4
- MANE Select transcript
- ENST00000160827.9NM_007317.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads KIF22 yet. The test sequences your whole genome, so your data includes it all the same.
How KIF22 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.1 kb of the gene's 14.6 kb; 1,998 of those bases code for the protein.
How a genome test reads KIF22
5
positions in KIF22 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 14.6 kb of KIF22, introns included, not only the 2.1 kb of exons.
Traits linked to KIF22
The Human Phenotype Ontology lists these as features of the rare conditions KIF22 can cause. Each trait's page lists the other genes linked to it.
Abnormality of limbs
- Abnormality of limbs
- Abnormality of the long bone of foot
- Abnormally shaped wrist bones
- Absent/small extremities
- Irregular wide portion of a long bone
- Knock knees
- Metaphyseal striations
- Outward bow-leggedness
Show 20 more traits
- Slender finger
- Slender long bones of hand
- Elbow flexion contracture
- Flat end part of innermost thighbone
- Hip dislocation
- Partial hip dislocation
- Wind-swept deformity of the knees
- Broad outermost finger bone
- Delayed bone maturation of the knee cap
- Dislocated hip since birth
- Dislocated radial head
- Flared wide portion of long bone
- Long innermost finger bone
- Long outermost bone of finger
- Narrow neck of thigh bone
- Slender innermost bone of finger
- Slender outermost bone of finger
- Small carpal bones
- Small innermost thighbone end part
- Streak increase in bone density in wide portion of wide bone
Abnormality of the musculoskeletal system
- Abnormal development of end part of bone
- Abnormal skeletal development
- Double-Jointed
- Abnormal curve of the backbone
- Delayed maturation of end part of long bone
- Flattened vertebrae
- Fragmented end part of bone
- Hunched back
Show 19 more traits
- Hypermobility of all joints
- Multiple joint dislocation
- Neonatal short-trunk short stature
- Premature osteoarthritis
- Radial head subluxation
- Scoliosis
- Spondyloepimetaphyseal dysplasia
- Kyphoscoliosis
- Thoracolumbar kyphosis
- Caudal interpedicular narrowing
- Delayed bone maturation of end part of digital bone
- Flat end part of bone
- Generalized decreased muscle tone
- Irregular end part of long bone
- Irregular vertebral endplates
- Large joint dislocations
- Low muscle tone
- Posterior scalloping of vertebral bodies
- Small end part of bone
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). KIF22 gene: kinesin family member 22. Retrieved 17 October 2026, from https://dantelabs.com/genes/kif22
Dante Labs. KIF22 gene: kinesin family member 22 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kif22
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