Gene
EIF4A3
eukaryotic translation initiation factor 4A3
- HGNC 18683↗(opens in a new tab)
- Ensembl gene ENSG00000141543↗(opens in a new tab)
- NCBI Gene 9775↗(opens in a new tab)
Summary
- Cytogenetic location
- 17q25.3
- Coordinates
- Chromosome 17: 80,134,369–80,147,128 (GRCh38)
- Exons
- 12 exons across 12.8 kb
- Protein
- 411 amino acids
- Also known as
- KIAA0111, EIF4AIII, Fal1
- Previous symbols
- DDX48
- MANE Select transcript
- ENST00000649764.2NM_014740.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read EIF4A3, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads EIF4A3 yet. The test sequences your whole genome, so your data includes it all the same.
How EIF4A3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.5 kb of the gene's 12.8 kb; 1,236 of those bases code for the protein.
Traits linked to EIF4A3
The Human Phenotype Ontology lists these as features of the rare conditions EIF4A3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of limbs
- Short big toe
- Underdeveloped outer large forearm bone
- Absent/small thumb
- Club feet
- Mesomelic leg shortening
- Short 5th finger
- Short calf bone
- Short thumb
Show 15 more traits
- Small hypothenar eminence
- Small thenar eminence
- Tibial deviation of toes
- Attachment of thumb close to wrist
- Curvature of little finger
- Mesomelic arm shortening
- Short shinbone
- Small heel bone
- Acetabular dysplasia
- Fused 4th-5th long bones of hand
- Hip dislocation
- Partial hip dislocation
- Radial deviation of the hand
- Short finger bones
- Shortened long bone of hand
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). EIF4A3 gene: eukaryotic translation initiation factor 4A3. Retrieved 17 October 2026, from https://dantelabs.com/genes/eif4a3
Dante Labs. EIF4A3 gene: eukaryotic translation initiation factor 4A3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/eif4a3
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks