Traits

Traits linked to RRAGD

Ras related GTP binding D

The Human Phenotype Ontology links 28 traits to RRAGD, by body system: features seen in people with one of the gene's rare conditions.

Laboratory abnormality

Trait	How often it is seen
Low blood magnesium levels	Always
Elevated urine calcium levels	Very often (80–99%)
Hypermagnesiuria	Very often (80–99%)
Hypokalemic metabolic alkalosis	Very often (80–99%)
Low blood calcium levels	Very often (80–99%)
Excess fluid in lungs	Often (30–79%)
High urine prostaglandin levels	Often (30–79%)
Low blood potassium levels	Often (30–79%)
Low blood sodium levels	Often (30–79%)
Metabolic acidosis	Often (30–79%)

Abnormality of the cardiovascular system

Trait	How often it is seen
Elevated left ventricular end-diastolic diameter	Very often (80–99%)
Reduced left ventricular ejection fraction	Very often (80–99%)
Stretched and thinned heart muscle	Very often (80–99%)
Cardiac failure	Often (30–79%)
Fluid around heart	Often (30–79%)
Sudden cardiac death	Often (30–79%)

Abnormality of the nervous system

Trait	How often it is seen
Hyperactive movements	Often (30–79%)
Hypocalcemic tetany	Often (30–79%)
Myoclonic spasms	Often (30–79%)
Epilepsy	Sometimes (5–29%)
Grand mal seizures	Sometimes (5–29%)

Abnormality of the genitourinary system

Trait	How often it is seen
Abnormal renal tubular resorption	Often (30–79%)
Increased calcium level in kidney	Often (30–79%)
Increased urine output	Often (30–79%)

Abnormality of the digestive system

Trait	How often it is seen
Hepatic calcification	Often (30–79%)

Abnormality of the endocrine system

Trait	How often it is seen
Elevated plasma aldosterone	Often (30–79%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Intermittent involuntary muscle spasm	Often (30–79%)

Constitutional symptom

Trait	How often it is seen
Joint pain	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to RRAGD and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test