Trait
Motor regression
Loss of previously achieved motor skills, as manifested by loss of developmental motor milestones.
Summary
- Also called
- Regression of motor skills
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Motor regression, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test21 genes linked to Motor regression
Changes in these genes cause rare conditions in which Motor regression is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| COX15cytochrome c oxidase assembly factor COX15 | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| GLB1galactosidase beta 1 | Always | In 1 condition |
| MALmal, T cell differentiation protein (MAL blood group) | Always | In 1 condition |
| NFU1NFU1 iron-sulfur cluster scaffold | Always | In 1 condition |
| NGLY1N-glycanase 1 | Always | In 1 condition |
| OPA1OPA1 mitochondrial dynamin like GTPase | Always | In 1 condition |
| POLR3KRNA polymerase III subunit K | Always | In 1 condition |
| SNAPC4small nuclear RNA activating complex polypeptide 4 | Always | In 1 condition |
| ADH5alcohol dehydrogenase 5 (class III), chi polypeptide | Often (30–79%) | In 1 condition |
| CLN8CLN8 transmembrane ER and ERGIC protein | Often (30–79%) | In 1 condition |
| EPRS1glutamyl-prolyl-tRNA synthetase 1 | Often (30–79%) | In 1 condition |
| MSL2MSL complex subunit 2 | Often (30–79%) | In 1 condition |
| POLR3GLRNA polymerase III subunit GL | Often (30–79%) | In 1 condition |
| SELENOIselenoprotein I | Often (30–79%) | In 1 condition |
| STN1STN1 subunit of CST complex | Often (30–79%) | In 1 condition |
| TRAPPC6Btrafficking protein particle complex subunit 6B | Often (30–79%) | In 1 condition |
| DPH5diphthamide biosynthesis 5 | Sometimes (5–29%) | In 1 condition |
| HSD17B4hydroxysteroid 17-beta dehydrogenase 4 | Sometimes (5–29%) | In 1 condition |
| LRPPRCleucine rich pentatricopeptide repeat containing | Sometimes (5–29%) | In 1 condition |
| NDUFA6NADH:ubiquinone oxidoreductase subunit A6 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks