Trait
Encephalomalacia
Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury.
Summary
- Also called
- Cerebral softening
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test16 genes linked to Encephalomalacia
Changes in these genes cause rare conditions in which Encephalomalacia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| MAN2B2mannosidase alpha class 2B member 2 | Always | In 1 condition |
| MICU1mitochondrial calcium uptake 1 | Always | In 1 condition |
| MOCS3molybdenum cofactor synthesis 3 | Always | In 1 condition |
| SPOUT1SPOUT domain containing methyltransferase 1 | Always | In 1 condition |
| ANGPTL6angiopoietin like 6 | Sometimes (5–29%) | In 1 condition |
| COL3A1collagen type III alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| ENGendoglin | Sometimes (5–29%) | In 1 condition |
| TGFBR3transforming growth factor beta receptor 3 | Sometimes (5–29%) | In 1 condition |
| THSD1thrombospondin type 1 domain containing 1 | Sometimes (5–29%) | In 1 condition |
| ZNFX1zinc finger NFX1-type containing 1 | Sometimes (5–29%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Rarely (1–4%) | In 1 condition |
| ALX4ALX homeobox 4 | Rarely (1–4%) | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Rarely (1–4%) | In 1 condition |
| IARS2isoleucyl-tRNA synthetase 2, mitochondrial | Rarely (1–4%) | In 1 condition |
| MSX2msh homeobox 2 | Rarely (1–4%) | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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