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Gene

ASCC1

activating signal cointegrator 1 complex subunit 1

Summary

Cytogenetic location
10q22.1
Coordinates
Chromosome 10: 72,096,032–72,216,276 (GRCh38)
Exons
10 exons across 120.2 kb
Protein
357 amino acids
Also known as
CGI-18, ASC1p50, Em:AC022392.3, p50
MANE Select transcript
ENST00000672957.1NM_001198800.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ASCC1 yet. The test sequences your whole genome, so your data includes it all the same.

How ASCC1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where ASCC1 sits. ASCC1 and 10 genes near it on chromosome 10, from 71,656,154 to 72,656,153.Chromosome 1010q22.1p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.371.8 Mb72 Mb72.2 Mb72.4 Mb72.6 MbCDH23: 71,396,884–71,815,947, forward strandCDH23C10orf105: 71,711,701–71,737,838, reverse strandC10orf105VSIR: 71,747,556–71,773,608, reverse strandVSIRPSAP: 71,816,026–71,851,388, reverse strandPSAPCHST3: 71,963,538–72,019,147, forward strandCHST3SPOCK2: 72,059,016–72,089,032, reverse strandSPOCK2ASCC1: 72,096,032–72,216,276, reverse strandASCC1ANAPC16: 72,215,651–72,235,860, forward strandANAPC16DDIT4: 72,273,919–72,276,039, forward strandDDIT4DNAJB12: 72,332,830–72,355,167, reverse strandDNAJB12MICU1: 72,355,297–72,626,134, reverse strandMICU1Diagram of ASCC1: 10 exons on the reverse strand of chromosome 10Exon 8: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 5: 5 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 10: 72,096,032–72,097,450, 1,419 basesExon 9: 72,128,082–72,128,167, 86 basesExon 8: 72,133,057–72,133,181, 125 basesExon 7: 72,152,869–72,152,988, 120 basesExon 6: 72,161,538–72,161,674, 137 basesExon 5: 72,196,811–72,196,989, 179 basesExon 4: 72,203,427–72,203,524, 98 basesExon 3: 72,210,732–72,210,831, 100 basesExon 2: 72,213,187–72,213,331, 145 basesExon 1: 72,216,207–72,216,276, 70 bases109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 120.2 kb; 1,074 of those bases code for the protein.

How a genome test reads ASCC1

14

positions in ASCC1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 120.2 kb of ASCC1, introns included, not only the 2.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ASCC1 gene: activating signal cointegrator 1 complex subunit 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/ascc1

Vancouver

Dante Labs. ASCC1 gene: activating signal cointegrator 1 complex subunit 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ascc1

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