Trait
High blood phosphate levels
Clinical name: Hyperphosphatemia
The concentration of phosphate ion in the blood circulation is above the upper limit of normal.
Summary
- Also called
- Elevated phosphate ion concentration, Elevated phosphate ion level, Elevated phosphate ion level in blood, Increased phosphate ion concentration, Increased phosphate ion level, Increased phosphate ion level in blood
- Body system
- Laboratory abnormality
Reference genomeGRCh38hg38
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Get my Genome Test21 genes linked to High blood phosphate levels
Changes in these genes cause rare conditions in which High blood phosphate levels is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GALNT3polypeptide N-acetylgalactosaminyltransferase 3 | Always | In 1 condition |
| KLklotho | Always | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Always | In 1 condition |
| PTHparathyroid hormone | Always | In 1 condition |
| TBCEtubulin folding cofactor E | Always | In 2 conditions |
| GCM2GCM transcription factor 2 | Very often (80–99%) | In 2 conditions |
| GNASGNAS complex locus | Very often (80–99%) | In 7 conditions |
| STX16syntaxin 16 | Very often (80–99%) | In 2 conditions |
| CACNA1Scalcium voltage-gated channel subunit alpha1 S | Often (30–79%) | In 1 condition |
| CASRcalcium sensing receptor | Often (30–79%) | In 2 conditions |
| CLDN16claudin 16 | Often (30–79%) | In 1 condition |
| FAM111AFAM111 trypsin like peptidase A | Often (30–79%) | In 2 conditions |
| GNA11G protein subunit alpha 11 | Often (30–79%) | In 1 condition |
| RYR1ryanodine receptor 1 | Often (30–79%) | In 3 conditions |
| FBXO22F-box protein 22 | Sometimes (5–29%) | In 1 condition |
| LPIN1lipin 1 | Sometimes (5–29%) | In 1 condition |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Sometimes (5–29%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Sometimes (5–29%) | In 1 condition |
| OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | Sometimes (5–29%) | In 1 condition |
| GNAS-AS1GNAS antisense RNA 1 | Not recorded | In 1 condition |
| TNFRSF11BTNF receptor superfamily member 11b | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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