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Trait

Increased female sex drive

Clinical name: Increased female libido

Elevated sexual desire in female

HPO HP:0030019

Summary

Body system
Abnormality of the genitourinary systemAbnormality of the nervous system

19 genes linked to Increased female sex drive

Changes in these genes cause rare conditions in which Increased female sex drive is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
CHD7chromodomain helicase DNA binding protein 7Very often (80–99%)In 1 condition
DUSP6dual specificity phosphatase 6Very often (80–99%)In 1 condition
EMX2empty spiracles homeobox 2Very often (80–99%)In 1 condition
FGF17fibroblast growth factor 17Very often (80–99%)In 1 condition
FGF8fibroblast growth factor 8Very often (80–99%)In 1 condition
FGFR1fibroblast growth factor receptor 1Very often (80–99%)In 1 condition
GNRH1gonadotropin releasing hormone 1Very often (80–99%)In 1 condition
GNRHRgonadotropin releasing hormone receptorVery often (80–99%)In 1 condition
HS6ST1heparan sulfate 6-O-sulfotransferase 1Very often (80–99%)In 1 condition
KISS1KiSS-1 metastasis suppressorVery often (80–99%)In 1 condition
KISS1RKISS1 receptorVery often (80–99%)In 1 condition
NHLH2nescient helix-loop-helix 2Very often (80–99%)In 1 condition
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factorVery often (80–99%)In 1 condition
PROK2prokineticin 2Very often (80–99%)In 1 condition
PROKR2prokineticin receptor 2Very often (80–99%)In 1 condition
SPRY4sprouty RTK signaling antagonist 4Very often (80–99%)In 1 condition
TAC3tachykinin precursor 3Very often (80–99%)In 1 condition
TACR3tachykinin receptor 3Very often (80–99%)In 1 condition
WDR11WD repeat domain 11Very often (80–99%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Female sexual dysfunctionIncreased libido

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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